ArticleAnnals of hepato-biliary-pancreatic surgery2026
New-onset diabetes after distal pancreatectomy-findings from a national cohort study.
Article in Annals of hepato-biliary-pancreatic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Backgrounds/Aims: Pancreatic resection is associated with a high frequency of postoperative new-onset diabetes mellitus (NODM). The present study aimed to quantify the rate and investigate potential risk factors for NODM after distal pancreatectomy. Methods: Data on patients undergoing distal pancreatectomy between 2010 and 2020 were obtained from the Swedish National Pancreatic and Periampullary Cancer Registry and cross-referenced with the Swedish National Diabetes Register. Uni- and multivariable competing risk regression analyses were conducted to model sub-distribution hazards (SHR) of NODM between groups. Results: A total of 1,034 patients were included, with 290 (28%) developing NODM postoperatively. The risk of NODM was reduced for female patients (SHR 0.73, Conclusions: NODM was common among patients after distal pancreatectomy, with several patient and surgical factors influencing risk. A minimally-invasive approach was associated with a lower risk of NODM after surgery. This association warrants further study, but should be interpreted cautiously due to potential selection bias and residual confounding, but it warrants further study.
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