ArticleBMJ paediatrics open2026
Procalcitonin-platelet ratio as a predictor of severity of necrotising enterocolitis in preterm infants.
Article in BMJ paediatrics open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A retrospective cohort study included preterm infants (<37 weeks of gestation, <2500 g) diagnosed with necrotising enterocolitis (NEC) admitted to Wahidin Sudirohusodo Hospital's neonatal intensive care unit from January 2023 to December 2024. Forty-seven infants were analysed; procalcitonin (PCT) levels were significantly higher, and platelet (PLT) counts were significantly lower in the severe group compared with the mild-moderate group (p<0.05). The procalcitonin-to-platelet (PCT/PLT) ratio was notably elevated in severe NEC cases (p<0.05). Receiver operating characteristic analysis indicated area under the curve (AUC) values of 0.786 for PCT, 0.126 for PLT and 0.916 for the PCT/PLT ratio. The sensitivity and specificity of the PCT/PLT ratio are 0.862 and 0.833, respectively.
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