Evidence map›Paper›PMID 42527107›Full record

ArticleBMJ paediatrics open2026

Implementing a parent-mediated intervention for toddlers with ASD within the Chinese child healthcare system: a real-world study.

Huiping Li, Xiang Long, Xiuqing Huang, Shu Liu, Zhuhong Yang, Chun Chen, Qing Lou, Xiubin Tong, Xiu Xu

Abstract readMulticenter Study
In one paragraph

Article in BMJ paediatrics open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huiping LiDepartment of Child Health Care, Children's Hospital of Fudan University, Shanghai, Shanghai, China lihuiping@fudan.edu.cn xuxiu@fudan.edu.cn.ORCID http://orcid.org/0000-0002-4554-2247
Xiang LongDepartment of Child Health Care, Shanghai Jiading Maternal and Child Health Hospital, Shanghai, Shanghai, China.
Xiuqing HuangDepartment of Child Health Care, Children's Hospital of Fudan University at Xiamen, Xiamen, Fujian, China.
Shu LiuDepartment of Child Health Care, Children's Hospital of Fudan University at Xiamen, Xiamen, Fujian, China.
Zhuhong YangDepartment of Child Health Care, Children's Hospital of Fudan University at Xiamen, Xiamen, Fujian, China.
Chun ChenDepartment of Child Health Care, Children's Hospital of Fudan University at Xiamen, Xiamen, Fujian, China.
Qing LouChildren's Hospital of Fudan University at Xiamen, Xiamen, Fujian, China.
Xiubin TongDepartment of Child Health Care, Children's Hospital of Fudan University at Xiamen, Xiamen, Fujian, China.
Xiu XuDepartment of Child Health Care, Children's Hospital of Fudan University, Shanghai, Shanghai, China lihuiping@fudan.edu.cn xuxiu@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBehavioural interventions remain the cornerstone of evidence-based practice for addressing the core symptoms of autism spectrum disorder (ASD). The Skill Training Program for Parents with ASD Children (STPAC) is a group intervention programme for parents and the first parent-mediated intervention programme developed by Chinese clinical practitioners. This study was conducted to evaluate the feasibility and effectiveness of STPAC within the context of routine child healthcare services in China.

methodsThis is a real-world, multi-site implementation study employed a single-arm, pre-post design. Between July 2023 and June 2025, 128 families of toddlers (aged 18-54 months) with suspected or diagnosed ASD were enrolled from two child healthcare settings. Participants received the 8-week, group-based parent training programme, which integrated didactic lessons, video modelling and individualised coaching. Outcomes were assessed at baseline and post-intervention using parent-reported measures: the Knowledge of Autism Intervention Questionnaire (KAIQ), the Communication and Symbolic Behavior Scales Developmental Profile (CSBS DP) and the Parenting Stress Index-Short Form (PSI-SF). Statistical analysis included paired-samples t-tests to evaluate within-group changes, with effect sizes (Cohen's d) calculated to quantify the magnitude of improvement.

resultsParental knowledge of autism intervention strategies increased substantially (mean improvement=6.26 points, p<0.001; d=1.17). Child communication and symbolic skills also improved, with the CSBS DP total score rising from 35.30 to 40.88 (p<0.001; d=0.99), representing an overall improvement rate of 85.7%. Furthermore, parenting stress decreased from clinically significant to normal levels (mean reduction=3.70 points, p=0.005). The intervention was equally effective across diverse family demographics, and baseline child communication ability was the strongest predictor of post-intervention gains.

conclusionsDespite an attrition rate of approximately 30%, STPAC demonstrated feasibility as a parent-mediated intervention delivered by trained local clinicians within routine child healthcare settings. Participation in the programme was associated with improvements in parental knowledge, child social communication and parenting stress. These findings provide preliminary evidence supporting the potential of STPAC to expand access to early ASD intervention, though confirmation in a randomised controlled trial is warranted.

Indexed as

Autism Spectrum DisorderBehavior TherapyParentsChild, PreschoolChinaEast Asian PeopleFeasibility StudiesFemaleHumansInfantMaleParentingChild PsychiatryDeveloping CountriesTherapeutics

Identifiers

PMID42527107
PMCPMC13422803

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.