ArticleExperimental eye research2026
Macrophages increase in corneal epithelium and stroma after photorefractive keratectomy-like corneal abrasion and amplify ocular pain responses in rats.
Deborah M Hegarty, Cody L Jiang, Clem Gunter, Destinee Semidey, Catherine W Morgans, Tally M Largent-Milnes, Sue A Aicher
Abstract read
In one paragraphArticle in Experimental eye research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Deborah M HegartyDepartment of Chemical Physiology & Biochemistry, Oregon Health & Science University, Portland, OR, USA.
Cody L JiangDepartment of Chemical Physiology & Biochemistry, Oregon Health & Science University, Portland, OR, USA.
Clem GunterDepartment of Chemical Physiology & Biochemistry, Oregon Health & Science University, Portland, OR, USA.
Destinee SemideyDepartment of Chemical Physiology & Biochemistry, Oregon Health & Science University, Portland, OR, USA.
Catherine W MorgansDepartment of Chemical Physiology & Biochemistry, Oregon Health & Science University, Portland, OR, USA.
Tally M Largent-MilnesDepartment of Pharmacology, University of Arizona, Tucson, AZ, USA.
Sue A AicherDepartment of Chemical Physiology & Biochemistry, Oregon Health & Science University, Portland, OR, USA. Electronic address: aichers@ohsu.edu.
Funding
Mechanisms of Pain and Photophobia in Migraine and Dry EyeU01EY034680 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SUE A AICHER, CATHERINE W MORGANS · 2022 to 2026
$4.5MHigh Performance Computing and Machine Learning Infrastructure for Oregon Life SciencesS10OD034224 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLROTT, KYLE · 2023 to 2023
$2.0MNEI NIH HHS U01 EY034680NIH HHS S10 OD034224
6 · The paper itselfAbstract
In a preclinical rat model that mimics initial stages of photorefractive keratectomy (PRK) we examined changes in the localization of CD68
Indexed as
Corneal InjuriesCorneal StromaEpithelium, CornealEye PainMacrophagesPhotorefractive KeratectomyAnimalsAntigens, CDAntigens, Differentiation, MyelomonocyticCD68 MoleculeDisease Models, AnimalFemaleMaleRatsRats, Sprague-DawleyWound HealingAntigens, CDAntigens, Differentiation, MyelomonocyticCD68 MoleculeCD68 protein, ratConfocal microscopyImmune cellsInjuryMorphologyOrbital tighteningPeripherySex differences
Identifiers
PMID42526682
PMCPMC13495947
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