Evidence map›Paper›PMID 42526058›Full record

ArticleGlobal spine journal2026

Comparison of Hospital Mortality and Risk Factors in Conservative and Surgical Treatment of Pyogenic Vertebral Osteomyelitis: A Nationwide Analysis of 49,951 Cases in Germany.

Melanie Ardelt, Josina Straub, Jonas Krückel, Adriana Palacio Giraldo, Markus Rupp, Markus Loibl, Volker Alt, Dietmar Dammerer, Siegmund Lang

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Article in Global spine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Melanie ArdeltDepartment of Orthopaedics and Traumatology, University Hospital Krems - NOE LGA, Karl Landsteiner University, Krems, Austria.ORCID 0000-0002-5050-0316
Josina StraubDepartment of Trauma Surgery, University Hospital Regensburg, Regensburg, Germany.
Jonas KrückelDepartment of Trauma Surgery, University Hospital Regensburg, Regensburg, Germany.ORCID 0009-0002-3057-2600
Adriana Palacio GiraldoDepartment of Orthopaedics and Traumatology, University Hospital Krems - NOE LGA, Karl Landsteiner University, Krems, Austria.
Markus RuppDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital Giessen, Giessen, Germany.
Markus LoiblDepartment of Spine Surgery, Schulthess Klinik, Zürich, Switzerland.
Volker AltDepartment of Trauma Surgery, University Hospital Regensburg, Regensburg, Germany.
Dietmar DammererDepartment of Orthopaedics and Traumatology, University Hospital Krems - NOE LGA, Karl Landsteiner University, Krems, Austria.
Siegmund LangDepartment of Trauma Surgery, University Hospital Regensburg, Regensburg, Germany.ORCID 0000-0003-0459-9092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study DesignRegistry-based retrospective cohort study.ObjectiveIdentify risk factors for in-hospital mortality in patients with vertebral osteomyelitis (VO) treated conservatively or surgically using a national dataset.MethodsHospital data from 2019 to 2023 were analyzed using the database of the German Institute for the Hospital Remuneration System (InEK). Cases were identified by ICD-10 codes M46.20-M46.59. Diagnosis-related groups (DRG) were used to analyze demographics and treatment.ResultsA total of 49,951 VO cases were identified, with an overall in-hospital mortality of 6.7%. The incidence of VO in Germany from 2020 to 2023 was 46.2 cases per 100,000 population. VO in the cervicothoracic (OR 2.31), thoracolumbar (OR 2.88), lumbosacral (OR 2.60) and multifocal (OR 3.93) regions was associated with increased in-hospital mortality. Conservative treatment was linked to higher mortality in intraspinal abscesses (OR 1.9) and multifocal disease (OR 2.29). In unadjusted, treatment-stratified analyses, surgical treatment was associated with higher in-hospital mortality in patients aged ≥65 years (OR 1.47) and ≥80 years (OR 1.56). Regarding pathogens, the highest mortality ORs were observed in patients infected with

Indexed as

in-hospital mortalitytreatment optionsvertebral osteomyelitis

Identifiers

PMID42526058
PMCPMC13420109

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