Evidence map›Paper›PMID 42525834›Full record

ArticleAmerican journal of physiology. Cell physiology2026

Mechanistic Modeling of MCUx Gatekeeping, Ca

Yisak D Asefa, Devanshi D Dave, Said H Audi, Dexuan Xie, Xiaowen Bai, Allen W Cowley, Ranjan K Dash

Abstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yisak D AsefaJoint Department of Biomedical Engineering, Marquette University-Medical College of Wisconsin, Milwaukee, WI, US.ORCID 0009-0005-8317-0041
Devanshi D DaveJoint Department of Biomedical Engineering, Marquette University-Medical College of Wisconsin, Milwaukee, WI, US.ORCID 0000-0002-9075-1718
Said H AudiJoint Department of Biomedical Engineering, Marquette University-Medical College of Wisconsin, Milwaukee, WI, US.ORCID 0000-0002-4887-604X
Dexuan XieDepartment of Mathematics, University of Wisconsin, Milwaukee, WI, US.ORCID 0000-0002-7072-6275
Xiaowen BaiDepartment of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, OH, US.ORCID 0000-0002-9342-4480
Allen W CowleyDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI, US.ORCID 0000-0002-0801-6248
Ranjan K DashJoint Department of Biomedical Engineering, Marquette University-Medical College of Wisconsin, Milwaukee, WI, US.ORCID 0000-0001-6751-0679

Funding

High Salt Remodels Renal Cortical and Proximal Tubular Metabolism: Metabolic Fuels, Oxidative Stress, and HypertensionR01HL151587 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Allen W Cowley, Ranjan K Dash · 2021 to 2026
$3.7M
SPECT Imaging and Computational Modeling for Assessment of Acute Lung InjuryR15HL129209 · NHLBI · MARQUETTE UNIVERSITY · PI SAID H AUDI · 2015 to 2026
$1.8M
Mitochondria and anesthetic-induced developmental neurotoxicityR35GM148177 · NIGMS · OHIO STATE UNIVERSITY · PI Xiaowen Bai · 2023 to 2026
$1.7M
HHS | National Institutes of Health (NIH) NIH R15-HL129209-04HHS | National Institutes of Health (NIH) NIH R35-GM148177-01HHS | National Institutes of Health (NIH) NIH RO1-HL151587-05National Science Foundation (NSF) NSF DMS 2153387NHLBI NIH HHS R01 HL151587NHLBI NIH HHS R15 HL129209NIGMS NIH HHS R35 GM148177
6 · The paper itself

Abstract

Mitochondrial Ca

Indexed as

Cytosolic-mitochondrial Ca2+ dynamicsMCUx gatingMICU1/2 regulationMitochondrial Ca2+ uptakeMitochondrial calcium uniporter complex (MCUx)

Identifiers

PMID42525834
PMCPMC13533480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.