Article in Diabetes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Tiffany T TerryDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-2729-6281
Eduardo D GiganteDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-1486-5377
Coralie M AlexandreDiabetes Center and Department of Medicine, University of California, San Francisco, San Francisco, CA.ORCID 0009-0004-2978-2648
Kathryn M BrewerDepartment of Biology, Indiana University-Indianapolis, Indianapolis, IN.ORCID 0009-0006-3498-4492
Xinyu YueDiabetes Center and Department of Medicine, University of California, San Francisco, San Francisco, CA.ORCID 0000-0002-6187-5906
Nicolas F BerbariDepartment of Biology, Indiana University-Indianapolis, Indianapolis, IN.ORCID 0000-0003-2863-1069
Christian VaisseDiabetes Center and Department of Medicine, University of California, San Francisco, San Francisco, CA.ORCID 0000-0003-4274-7033
Tamara CasparyDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-6579-7589
Funding
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
The Melanocortin-4 Receptor in Human ObesityR01DK060540 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2002 to 2026
$7.5M
Obesity in Ciliopathies: How Neuronal Primary Cilia Control AppetiteR01DK106404 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI REITER, JEREMY F, VAISSE, CHRISTIAN · 2016 to 2025
$6.6M
Training In Systems And Integrative Biology NeuroscienceT32NS096050 · NINDS · EMORY UNIVERSITY · PI Yoland Smith · 2016 to 2026
$3.9M
Functional characterization of obesity-associated OXTR enhancersR01DK124769 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, VAISSE, CHRISTIAN · 2020 to 2024
$3.7M
How Hedgehog Contributes to Centrally Mediated Energy Homeostasis?R01DK114008 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Nicolas F Berbari, Jeremy F Reiter · 2018 to 2026
$3.3M
Genetic Dissection of Signaling and CiliaR35GM148416 · NIGMS · EMORY UNIVERSITY · PI TAMARA J. CASPARY · 2023 to 2026
$2.1M
Genetic Dissection of Signaling and CiliaR35GM122549 · NIGMS · EMORY UNIVERSITY · PI CASPARY, TAMARA J. · 2017 to 2021
$2.0M
Mechanisms underlying Joubert syndrome related brain malformationsR01NS090029 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ANTON, EVA S, CASPARY, TAMARA J. · 2015 to 2018
$1.9M
Wide field-of-view Spinning Disk Confocal with Photoactivation and PhotobleachingS10OD017993 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THORN, KURT · 2015 to 2015
$274k
The Critical Role of Ciliary ARL13B in Controlling Energy HomeostasisF32DK137409 · NIDDK · EMORY UNIVERSITY · PI Tiffany T Terry · 2024 to 2026
$249k
Defining the relationship of ciliary Arl13b and SmoothenedF31NS106755 · NINDS · EMORY UNIVERSITY · PI GIGANTE, EDUARDO D. · 2019 to 2020
$91k
American Heart AssociationDivision of Diabetes, Endocrinology, and Metabolic Diseases F31DK142351Division of Diabetes, Endocrinology, and Metabolic Diseases F32DK137409Division of Diabetes, Endocrinology, and Metabolic Diseases R01DK060540Division of Diabetes, Endocrinology, and Metabolic Diseases R01DK106404Division of Diabetes, Endocrinology, and Metabolic Diseases R01DK114008Division of Diabetes, Endocrinology, and Metabolic Diseases R01DK124769Indiana University FellowshipLarry L. Hillblom FoundationNIDDK NIH HHS F31 DK142351NIDDK NIH HHS F32 DK137409NIDDK NIH HHS P30 DK098722NIDDK NIH HHS R01 DK060540NIDDK NIH HHS R01 DK106404NIDDK NIH HHS R01 DK114008NIDDK NIH HHS R01 DK124769NIGMS NIH HHS R35 GM122549NIGMS NIH HHS R35GM122549NIGMS NIH HHS R35 GM148416NIGMS NIH HHS R35GM148416NIH HHS S10 OD017993NINDS NIH HHS F31 NS106755NINDS NIH HHS F31NS106755NINDS NIH HHS R01 NS090029NINDS NIH HHS R01NS090029NINDS NIH HHS T32 NS096050NINDS NIH HHS T32NS096050
6 · The paper itself
Abstract
article highlightsThe molecular mechanisms by which primary cilia regulate energy homeostasis remain poorly understood. Here, we evaluated whether the ciliary GTPase ARL13B regulates energy homeostasis and whether its localization to cilia is required to control body weight and feeding. Using genetic tools to isolate cilia-specific functions, we found that systemic exclusion of ARL13B from cilia causes hyperphagia and obesity in mice and that ciliary ARL13B is required in the nervous system for weight control. These findings identify ciliary ARL13B as a key regulator of energy homeostasis, contributing to our understanding of how primary cilia act as metabolic signaling hubs.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Ciliary ARL13B Is Essential for Body Weight Regulation in Mice. · full record | OpenQuestion