Evidence map›Paper›PMID 42525547›Full record

ArticleAIDS (London, England)2026

Parallel declines in antiretroviral therapy adherence by dried blood spot and electronic monitoring in Cape Town, South Africa.

Christopher M Ferraris, Paul A D'Avanzo, Justin Knox, Lauren Jennings, Catherine Orrell, Robert H Remien

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher M FerrarisNew York State Psychiatric Institute, New York, New York.
Paul A D'AvanzoRutgers School of Public Health, Rutgers University, New Brunswick, New Jersey.
Justin KnoxNew York State Psychiatric Institute, New York, New York.
Lauren JenningsDesmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Department of Medicine, University of Cape Town.
Catherine OrrellDesmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Department of Medicine, University of Cape Town.
Robert H RemienNew York State Psychiatric Institute, New York, New York.

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
Use of ARV Drug Levels in DBS to Assess and Manage ART Adherence in South AfricaR01AI122300 · NIAID · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI ORRELL, CATHERINE, REMIEN, ROBERT H · 2016 to 2020
$4.6M
NIAID NIH HHS R01 AI122300NIMH NIH HHS P30 MH043520
6 · The paper itself

Abstract

Among 250 adults with HIV (median age 34 years, IQR 27-42; 78% women), tenofovir diphosphate (TFV-DP) concentrations in dried blood spots and electronic adherence declined over 12 months. Mean TFV-DP fell from 1219 to 939 fmol/punch in men and 1148 to 894 in women, while electronic adherence declined from 65 to 49% in men and from 62 to 52% in women. Visit predicted declines in TFV-DP (F = 7.17, P < 0.001) and electronic adherence (F = 2.57, P = 0.003).

Indexed as

AdenineAnti-HIV AgentsAnti-Retroviral AgentsDried Blood Spot TestingDrug MonitoringHIV InfectionsMedication AdherenceOrganophosphatesAdultDigital HealthFemaleHumansMaleSouth AfricaAdenineAnti-HIV AgentsAnti-Retroviral AgentsOrganophosphatestenofovir diphosphate

Identifiers

PMID42525547
PMCPMC13574289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.