Evidence map›Paper›PMID 42525187›Full record

ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2026

A cross-sectional study of pulpal oxygen saturation in permanent incisors affected by molar incisor hypomineralisation (MIH).

T C de Almeida Dos Santos, M J D Gallo, A B de Souza Ramos, A A Leandro Junior, A De Rossi, F W G de Paula E Silva, M D Sousa-Neto, C Estrela, F K de Carvalho, A M de Queiroz

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Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

T C de Almeida Dos SantosFaculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil. thaliasantos@usp.br.
M J D GalloFaculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
A B de Souza RamosFaculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
A A Leandro JuniorFaculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
A De RossiFaculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
F W G de Paula E SilvaFaculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
M D Sousa-NetoFaculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.
C EstrelaUniversidade Federal de Goiás, Goiânia, Brazil.
F K de CarvalhoFaculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil. fabricio_kc@forp.usp.br.
A M de QueirozFaculdade de Odontologia de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate pulpal oxygen saturation (SaO₂) in permanent incisors affected by molar incisor hypomineralisation (MIH) compared with sound permanent incisors in children.

methodsThis cross-sectional study included 112 MIH-affected and 112 sound permanent incisors from children aged 6-12 years. Clinical examination was performed in all teeth, and periapical radiographs were obtained for MIH-affected incisors to exclude pathology and assess root development. Pulpal oxygen saturation was measured using pulse oximetry. Data were analysed using a mixed-effects linear model accounting for clustering of multiple teeth within the same individual. Complementary non-parametric analyses were also performed.

resultsMIH-affected incisors showed lower SaO₂ than controls (mean difference: 1.37%; 95% CI 0.90-1.84; p < 0.001). The intraclass correlation coefficient (ICC = 0.18) indicated moderate within-subject clustering. No significant differences in SaO₂ were observed according to root development stage (p = 0.45).

conclusionMIH-affected incisors exhibited slightly lower SaO₂ compared with sound teeth. Although statistically significant, the small magnitude of this difference limits its immediate clinical relevance and should be interpreted with caution.

Indexed as

ChildrenDental radiographyEnamel hypomineralisationMolar incisor hypomineralisationOxygen saturationPaediatric dentistry

Identifiers

PMID42525187

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.