Evidence map›Paper›PMID 42525179›Full record

ArticleGeroScience2026

Longitudinal association between dietary quality trajectories and cognitive frailty in older adults: a 12-year study of the TIGER cohort.

Ting-I Lee, Bo-Yu Hsiao, Te-Hsuan Huang, Ling-Wei Chen, Yi-Chun Chou, Meei-Shyuan Lee, Jeng-Min Chiou, Yen-Ching Chen, Jen-Hau Chen

Abstract read
PubMed Publisher
In one paragraph

Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ting-I LeeInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, No. 17, Xu-Zhou Road, Taipei, 10055, Taiwan.
Bo-Yu HsiaoInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, No. 17, Xu-Zhou Road, Taipei, 10055, Taiwan.
Te-Hsuan HuangInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, No. 17, Xu-Zhou Road, Taipei, 10055, Taiwan.
Ling-Wei ChenInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, No. 17, Xu-Zhou Road, Taipei, 10055, Taiwan.
Yi-Chun ChouDepartment of Geriatrics and Gerontology, National Taiwan University Hospital, Taipei, Taiwan.
Meei-Shyuan LeeCollege of Public Health, National Defense Medical University, Taipei, Taiwan.
Jeng-Min ChiouInstitute of Statistics and Data Science, National Taiwan University, Taipei, Taiwan.
Yen-Ching ChenInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, No. 17, Xu-Zhou Road, Taipei, 10055, Taiwan. karenchen@ntu.edu.tw.ORCID http://orcid.org/0000-0002-8159-7202
Jen-Hau ChenDepartment of Geriatrics and Gerontology, National Taiwan University Hospital Yunlin Branch, No. 95, Xuefu Rd., Yunlin County, 632007, Taiwan. jhhchen@ntu.edu.tw.ORCID http://orcid.org/0000-0002-7141-1582

Funding

National Science and Technology Council 100-2314-B-002-103National Science and Technology Council 101-2314-B-002-126-MY3National Science and Technology Council 103-2314-B-002-033-MY3National Science and Technology Council 104-2314-B-002-038-MY3National Science and Technology Council 107-2314-B-002-186-MY3National Science and Technology Council 107-2314-B-002-230National Science and Technology Council 108-2314-B-002-128-MY2National Science and Technology Council 110-2314-B-002-068National Science and Technology Council 110-2314-B-002-129-MY3National Science and Technology Council 111-2314-B-002-090-MY3National Science and Technology Council 113-2314-B-002-188-MY3National Science and Technology Council 113-2621-M-002-020National Science and Technology Council 114-2314-B-002-062-MY3
6 · The paper itself

Abstract

The effect of dietary quality trajectories on cognitive frailty in older adults has not been explored previously. This population-based study examines this association. Participants were recruited between 2011 and 2013 and followed through 2022 (median follow-up: 7.6 years). The study included 519 older adults, with dietary quality assessed at four time points and cognitive frailty evaluated at five time points. Dietary intake was assessed by food frequency questionnaires, and dietary quality trajectories were identified using growth mixture modeling based on the modified Alternative Healthy Eating Index. A battery of psychoneurological tests was used to evaluate global and domain-specific cognition. Physical frailty was measured using modified Fried's frailty phenotype. Cognitive frailty was defined as the coexistence of cognitive impairment and physical frailty and categorized into six ordinal levels according to combinations of cognitive and frailty status. Generalized linear mixed models were utilized to examine the relationship between trajectories of dietary quality and cognitive frailty adjusting for important covariates. Participants' baseline mean age was 72.7 years. Compared with Relatively Lower trajectory, Relatively Higher dietary quality trajectory was associated with traditional cognitive frailty (adjusted odds ratio (aOR) = 0.62) and impaired memory-frailty (aOR = 0.48-0.50), whereas Hill-Shaped trajectory was associated only with impaired memory-frailty (aOR = 0.60). Valley-Shaped trajectory was consistently associated with impaired memory-frailty (aOR = 0.48-0.56). Based on stratified analyses, these associations mainly became more evident in participants aged ≥ 75 years, men, those with normal body mass index (18.5-24 kg/m

Indexed as

Cognitive domainsCognitive frailtyDietary qualityTaiwan Initiative for Geriatric Epidemiological Research (TIGER)Trajectory analysis

Identifiers

PMID42525179

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.