Evidence map›Paper›PMID 42525117›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2026

Disseminated sporotrichosis with orbital osteomyelitis in a child: a case report.

Fabiana Bononi do Carmo, Kimberly Souza Rocha, Caio Vinícius Luís, Aída de Fátima Thomé Barbosa Gouvea, Daisy Maria Machado, Ana Isabel Melo Pereira Monteiro, Érica Regina Cruz Paulino, Marina Gomes Pereira Sardinha, Kelly Simone Almeida Cunegundes, Paulo Gois Manso and 6 more

Abstract readCase Reports
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Fabiana Bononi do CarmoUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-2088-4934
Kimberly Souza RochaUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-9328-9752
Caio Vinícius LuísUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-6444-9614
Aída de Fátima Thomé Barbosa GouveaUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0962-4445
Daisy Maria MachadoUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1993-6442
Ana Isabel Melo Pereira MonteiroUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0009-0009-8412-8274
Érica Regina Cruz PaulinoUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0009-0000-0748-3082
Marina Gomes Pereira SardinhaUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1206-8945
Kelly Simone Almeida CunegundesUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-7153-6422
Paulo Gois MansoUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-9125-2355
Anderson Messias RodriguesUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0891-4563
Pedro Fiorini PucchiniUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0009-0004-8393-4526
Marcelo Luiz AbramczykUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-7787-3887
Maria Aparecida Gadiani FerrariniUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-8844-3567
Carolina Sanchez Aranda LagoUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-2187-8192
Regina Célia de Menezes SucciUniversidade Federal de São Paulo, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-4522-6292

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sporotrichosis is an infection caused by fungi of the Sporothrix complex that can affect both humans and animals. In most cases, it is a benign infection limited to the skin and subcutaneous tissue, rarely disseminating to other organs with systemic involvement. Diagnosis is based on clinical data, epidemiological data, and laboratory tests, with culture being considered the gold standard. The disease generally has a good prognosis and is usually resolved with appropriate antifungal treatment. This case report describes an atypical presentation of sporotrichosis with suppurative nodules and orbital bone involvement in an adolescent followed at the pediatric infectious diseases outpatient clinic of our institution. The patient was followed longitudinally for 12 months due to a lesion on the left upper back with lymphocutaneous involvement, which progressed to osteomyelitis of the left orbit. Deep lesion culture identified Sporothrix spp. The sporotrichosis was considered disseminated, and treatment with oral itraconazole for 12 months was initiated. Complete remission of both cutaneous and bone lesions occurred after five months of treatment. The patient was discharged from outpatient follow-up after one year.

Indexed as

Orbital DiseasesOsteomyelitisSporotrichosisAdolescentAntifungal AgentsFemaleHumansItraconazoleAntifungal AgentsItraconazole

Identifiers

PMID42525117
PMCPMC13405641

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.