Trial reportRevista da Associacao Medica Brasileira (1992)2026
The effectiveness of virtual reality-based exercises in patients with symptomatic knee osteoarthritis: randomized controlled study.
Trial report in Revista da Associacao Medica Brasileira (1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Myofascial Trigger Point-Augmented Acupuncture vs Conventional Acupuncture for Early- to Mid-Stage Knee Osteoarthritis: A Randomized Clinical Trial.Journal of pain research · 2026Trial
- Nocturnal Pain in Patients with Knee Osteoarthritis: A Single-Center Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Comparative Effectiveness of Low-Dose Intra-Articular Ozone Therapy for Pain and Functional Outcomes in Patients with Knee Osteoarthritis: A Retrospective Cohort Study.Journal of pain research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to investigate the effectiveness of adding non-immersive virtual reality-based exercise to a conventional rehabilitation program for pain, functionality, balance, and quality of life in patients with knee osteoarthritis.
methodsThis randomized controlled clinical trial involved 60 patients. Measurements were taken before and after treatment (at week 3). Visual analog scale, Western Ontario and McMaster Universities Osteoarthritis Index, and the Short Form-36 were measured. Postural Stability- Dynamic Overall Stability Index, Functional Reach Composite Score, and Clinical Test of Sensory Interaction on Balance-Composite Score were recorded using the Biodex Balance System.
resultsIn both groups, statistically significant improvements were observed in visual analog scale, Western Ontario and McMaster Universities Osteoarthritis Index, the Short Form-36 Physical Functioning, Postural Stability-Dynamic Overall Stability Index, Functional Reach Composite Score, and Clinical Test of Sensory Interaction on Balance-Composite Score scores in the post-intervention period (p<0.001). In both groups, statistically significant improvements were observed in all Short Form-36 subscales [Physical Functioning, Role Physical, Bodily Pain, General Health, Vitality, Social Functioning, Role Emotional, and Mental Health were observed during the post-intervention period (p<0.001)]. In the two-way mixed-methods repeated-measures analysis of variance analysis, the time effect was found to be significant in all Short Form-36 subdimensions (p<0.001). The group-time interaction was not significant in the "Role Physical" and "Mental Health" subdimensions (p=0.151 and p=0.604, respectively).
conclusionThe addition of virtual reality-based exercise to results in greater reductions in pain levels and improvements in disease-specific functional status and overall physical function, postural stability, dynamic balance, and sensory integration. Further improvements in quality of life across all subscales except for physical role limitations and mental health.
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Registered trials
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