Evidence map›Paper›PMID 42524990›Full record

ArticleCadernos de saude publica2026

[Clinical Research Action Plan in Brazil: analysis of its implementation process and main results, 2018-2025].

Giovanny Vinícius Araújo de França, Evandro de Oliveira Lupatini, Michelle Zanon Pereira, Raisa Breda Tôso Sfalsini, Andréa Leite Ribeiro, Karla Andreia Mette Waldrich, Jaqueline Chueke Pureza, João Paulo Alves Oliveira, Patrícia de Souza Boaventura, Luciana Hentzy Moraes and 2 more

Abstract readEnglish Abstract
In one paragraph

Article in Cadernos de saude publica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giovanny Vinícius Araújo de FrançaSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0000-0002-7530-2017
Evandro de Oliveira LupatiniSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0000-0001-6231-891X
Michelle Zanon PereiraSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0009-0007-3747-9376
Raisa Breda Tôso SfalsiniSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0009-0000-6683-9413
Andréa Leite RibeiroSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0000-0003-4917-4469
Karla Andreia Mette WaldrichSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0009-0006-4162-0865
Jaqueline Chueke PurezaSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0009-0003-7169-7984
João Paulo Alves OliveiraSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0000-0001-5020-0981
Patrícia de Souza BoaventuraSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0009-0004-4128-9565
Luciana Hentzy MoraesSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0000-0003-1994-2180
Meiruze Sousa FreitasSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0009-0001-5788-5917
Fernanda De NegriSecretaria de Ciência, Tecnologia e Inovação em Saúde, Ministério da Saúde, Brasília, Brasil.ORCID http://orcid.org/0000-0002-3197-5156

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the Clinical Research Action Plan in Brazil (PAPCB, acronym in Portuguese), established in 2018 by the Brazilian Ministry of Health. This ex post public policy evaluation study was based on documentary analysis for the 2018-2025 period. The six strategic axes of the PAPCB were considered: ethical regulation, sanitary regulation, scientific and technological promotion, training in clinical research, the Clinical Research National Network (RNPC, acronym in Portuguese), and knowledge management. The results showed significant advances in scientific promotion and professional training, with broad execution of the planned actions. The training of more than 45,000 professionals stands out in the training axis. The RNPC underwent restructuring, giving rise to the Brazilian Network of Clinical Research (RBPClin, acronym in Portuguese). However, structural challenges persist, such as the need to modernize Plataforma Brasil, improve knowledge management, and strengthen network collaboration. This study recommends the review and update of the PAPCB, incorporating strategies to overcome these gaps to consolidate the Brazilian scientific, technological, and institutional capacity in clinical research.

Indexed as

Biomedical ResearchBrazilHumans

Identifiers

PMID42524990
PMCPMC13411462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.