Evidence map›Paper›PMID 42524917›Full record

SynthesisActa cirurgica brasileira2026

Analgesic strategies in the management of postoperative pain following uterine artery embolization for symptomatic fibroids: a systematic review.

Manoela Massa Moura, Karen Ruggeri Saad, Edson Ferreira Gonçalves Junior, Larissa Freire Golveia Silveira, Henrique Pereira Castro, Antônio Felipe Neto, Paulo Fernandes Saad

Abstract readSystematic Review
In one paragraph

Synthesis in Acta cirurgica brasileira, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manoela Massa MouraUniversidade de Brasília - Faculty of Medicine - Medical course - Brasília (DF) - Brazil.ORCID http://orcid.org/0009-0002-7168-8343
Karen Ruggeri SaadUniversidade de Brasília - Faculty of Medicine - Department of Morphology - Brasília (DF) - Brazil.ORCID http://orcid.org/0000-0002-3904-9026
Edson Ferreira Gonçalves JuniorUniversidade de Brasília - University Hospital of Brasília - Brasília (DF) - Brazil.ORCID http://orcid.org/0000-0002-1442-3739
Larissa Freire Golveia SilveiraUniversidade de Brasília - University Hospital of Brasília - Brasília (DF) - Brazil.ORCID http://orcid.org/0009-0007-5898-3643
Henrique Pereira CastroUniversidade de Brasília - University Hospital of Brasília - Brasília (DF) - Brazil.ORCID http://orcid.org/0000-0002-7255-418X
Antônio Felipe NetoUniversidade de Brasília - University Hospital of Brasília - Brasília (DF) - Brazil.ORCID http://orcid.org/0009-0005-6878-6702
Paulo Fernandes SaadUniversidade de Brasília - University Hospital of Brasília - Brasília (DF) - Brazil.ORCID http://orcid.org/0000-0002-5328-2019

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify and compare anesthetic and analgesic strategies employed during uterine artery embolization for symptomatic leiomyomas, assessing their effectiveness in reducing postoperative pain and opioid use and evaluating complication rates.

methodsA systematic review was conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Searches were performed in PubMed, Embase, Web of Science, and Scientific Electronic Library Online. Randomized controlled trials and prospective cohort or case-control studies, published in the last 10 years, evaluating pain, opioid consumption, and/or complications, were included.

resultsThe total of 3,433 studies were screened, of which six met eligibility criteria. Superior hypogastric plexus block reduced pain and opioid use. Intra-arterial lidocaine decreased pain within 2-4 h and opioid consumption, with a transient effect; administration after vascular stasis was preferable. Controlled-release oxycodone reduced pain at 24 h and need for rescue medication without lowering mean consumption. Dexamethasone reduced pain at 12-24 h without impacting opioid use. No significant complications were reported.

conclusionIn the ischemic phase of post-uterine artery embolization pain, a superior hypogastric nerve block appears to provide the most consistent relief, with intra-arterial lidocaine representing an alternative when resources are limited. For the inflammatory phase, intravenous dexamethasone is the preferred option, whereas controlled-release oxycodone may be considered only in refractory cases.

Indexed as

AnalgesicsLeiomyomaPostoperative PainUterine Artery EmbolizationUterine NeoplasmsAnalgesics, OpioidAnesthetics, LocalFemaleHumansLidocaineNerve BlockPain MeasurementTreatment OutcomeAnalgesicsAnalgesics, OpioidAnesthetics, LocalLidocaine

Identifiers

PMID42524917
PMCPMC13379049

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.