ArticleCureus2026
The Treatment of Craniocervical Instability Using Regenerative Medicine Therapies: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Craniocervical instability (CCI) is a disorder caused by weakness of the stabilizing ligaments of the craniocervical junction, leading to abnormal motion between the skull and upper cervical spine. CCI can present with any combination of the following symptoms: cervical neck pain, dizziness, autonomic dysfunction, migraines, and radiculopathy/myelopathy. CCI is often associated with connective tissue disorders. We present the case of a 51-year-old woman with a history of rheumatoid arthritis and chronic neck pain, migraines, vertigo, and autonomic dysfunction who underwent a series of regenerative injection treatments alongside postural and chiropractic therapy. Symptomatic and structural improvement was achieved, suggesting a possible role for regenerative therapies in the treatment of CCI. However, further studies are needed to investigate the effects of regenerative therapies on CCI severity. Our primary objective in presenting this case is to continue the conversation regarding the treatment of CCI with regenerative therapies and to spur further research on the topic.
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