ArticleInternational journal of medical sciences2026
Long-Term Trends in Microbiology and Outcomes of Pediatric Deep Neck Infections: An 18-Year Study.
Article in International journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Importance: Pediatric deep neck infection (DNI) is a potentially life-threatening condition. However, contemporary large-scale data describing microbial etiology and outcomes remain limited. Understanding long-term pathogen trends is essential for guiding empiric antibiotic therapy and improving outcomes. Objective: To investigate temporal changes in bacterial pathogens, treatment strategies, and outcomes of pediatric DNI across an 18-year period. Main Outcomes and Measures: Demographics, comorbidities, treatment modalities, disease severity, and microbiological profiles were analyzed. Bacterial isolates were evaluated at genus and species levels, with methicillin-sensitive Results: Among 1,743 pediatric DNI cases (1,017 in 2006-2014; 726 in 2015-2023), antibiotic-only therapy increased (91.5% to 94.4%), surgical intervention decreased (8.5% to 5.7%), and no tracheostomies were performed. ICU admission declined (8.9% to 6.8%), mediastinal complications decreased (0.6% to 0%), and mortality remained 0.1%. Conclusions and Relevance: Over 18 years, pediatric DNI in Taiwan demonstrated a marked shift toward conservative, antibiotic-based management with sustained excellent outcomes. Concurrently, MRSA and anaerobes such as
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