Evidence map›Paper›PMID 42524606›Full record

ArticleInfectious diseases & immunity2026

Expert consensus on the clinical management of HIV late presentation.

Wei Lyu, Weiping Cai, Yaokai Chen, Mengjie Han, Yun He, Huiqin Li, Linghua Li, Ruichao Lu, Ping Ma, Lijun Sun and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infectious diseases & immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Characterization of immune reconstitution inflammatory syndrome in a Mexican cohort].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Wei LyuPeking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.
Weiping CaiGuangzhou Eighth People's Hospital, Guangzhou 510440, China.
Yaokai ChenChongqing Public Health Medical Center, Chongqing 400030, China.
Mengjie HanChinese Center for Disease Control and Prevention, Beijing 102206, China.
Yun HeShenzhen Third People's Hospital and The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518112, China.
Huiqin LiYunnan Provincial Hospital of Infectious Disease, Kunming 650301, China.
Linghua LiGuangzhou Eighth People's Hospital, Guangzhou 510440, China.
Ruichao LuLiuzhou Longtan Hospital of Guangxi Zhuang Autonomous Region, Liuzhou 545026, China.
Ping MaTianjin Second People's Hospital, Tianjin 300192, China.
Lijun SunBeijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Yongtao SunTangdu Hospital, Air Force Medical University, Xi'an 710032, China.
Hui WangShenzhen Third People's Hospital and The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518112, China.
Rugang WangDalian Public Health Clinical Center, Dalian 116037, China.
Ning WangChinese Center for Disease Control and Prevention, Beijing 102206, China.
Hongxia WeiThe Second Hospital of Nanjing, Nanjing 210037, China.
Tong ZhangBeijing You'an Hospital, Capital Medical University, Beijing 100069, China.
Hongxin ZhaoBeijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Qingxia ZhaoHenan Infectious Diseases Hospital, Zhengzhou 450015, China.
Yingquan ZhouLanzhou Pulmonary Hospital, Lanzhou 730071, China.
Fujie ZhangBeijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Taisheng LiPeking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the advancement of combination antiretroviral therapy (cART), the global number of new human immunodeficiency virus (HIV) infections and HIV-related mortality has significantly declined. However, the high proportion of "late presentation" (defined as presenting to care with a low CD4 cell count or AIDS-defining events) among HIV-infected individuals remains a significant challenge in HIV prevention and treatment. HIV late presentation is associated with increased clinical risk, complex management, and higher risk of transmission, and represents a significant barrier to achieving the "95-95-95" targets and ending the HIV epidemic. Currently, both nationally and internationally, there is a lack of specific clinical guidelines for this population. Therefore, the China Association for Promotion of Health Science and Technology convened experts in the field to discuss the definition, clinical characteristics, risks, and cART of late presenters based on the latest research evidence and clinical practices both domestically and internationally. Specific recommendations were formulated to guide healthcare professionals in their clinical practice.

Indexed as

Clinical managementCombination antiretroviral therapyHIVLate presentationRapid initiation

Identifiers

PMID42524606
PMCPMC13412706

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.