Evidence map›Paper›PMID 42524587›Full record

ReviewInfectious diseases & immunity2026

Unraveling chikungunya's viral tapestry through molecular mechanisms and clinical insights.

Huan Xu, Xinrui Gao, Sheng Huang, Hao Wang, Xiaoxuan Wu, Junqing Han, Guangyu Liang, Jie Peng, Shaohang Cai, Chunlin Chen and 1 more

Abstract readReview
In one paragraph

Review in Infectious diseases & immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Huan XuDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Xinrui GaoDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Sheng HuangDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Hao WangThe First School of Clinical Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Xiaoxuan WuDepartment of Communicable and Endemic Disease Control and Prevention, Haizhu District Center for Disease Control and Prevention, Guangzhou 510277, China.
Junqing HanDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Guangyu LiangDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jie PengDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Shaohang CaiDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Chunlin ChenDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Aili LuDepartment of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya fever (CHIKF) is an arthropod-borne viral disease caused by the chikungunya virus (CHIKV). Patients typically present with fever and symmetric distal polyarthralgia, which may progress to chronic joint sequelae. This review was conducted to systematically examine CHIKF's virological characteristics, immunopathogenic mechanisms, global and regional epidemiology, and clinical manifestations as well as diagnostic approaches and treatment options. CHIKV may be present in areas previously considered nonendemic, as increased international travel, high urban population densities, and favorable vector ecology facilitate viral transmission. Effective CHIKF control requires the implementation of enhanced surveillance, targeted vector control measures, and standardized clinical management protocols. Considering CHIKV's genomic diversity and immune-driven pathogenesis and the wide spectrum of acute and chronic disease conditions, continuous monitoring and adaptive control measures tailored to specific settings are required.

Indexed as

Chikungunya virusChinaImmunopathologyMosquito-borne diseasesVector control

Identifiers

PMID42524587
PMCPMC13412659

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.