Evidence map›Paper›PMID 42524426›Full record

ArticleCardiology research2026

Racial Disparities in Transcatheter Edge-to-Edge Repair Versus Open Mitral Valve Surgery: A Nationwide Analysis.

Ali Awad, Qusai Al Qudah, Joud Fahed, Mariam Chalhoub, M Chadi Alraies

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Article in Cardiology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ali AwadDepartment of Internal Medicine, Detroit Medical Center, Wayne State University, Detroit, MI, USA.
Qusai Al QudahDepartment of Medicine, University of Central Florida College of Medicine, Orlando, FL, USA.
Joud FahedDepartment of Medicine, Ascension Saint Agnes Hospital, Baltimore, MD, USA.
Mariam ChalhoubDepartment of Medicine, Case Western Reserve University, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
M Chadi AlraiesDepartment of Cardiovascular Medicine, Detroit Medical Center, Wayne State University, Detroit, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Racial disparities have been documented across multiple domains of cardiovascular care, yet data on mitral valve intervention remain limited. We examined racial differences in procedural selection and outcomes following transcatheter edge-to-edge repair (TEER) and open mitral valve surgery. Methods: Using the National Inpatient Sample (NIS, 2016-2022), we identified 26,456 adults undergoing mitral valve intervention. Multivariable regression models were used to assess racial differences in mortality, procedure type, length of stay, and charges, adjusting for demographics, comorbidities, hospital characteristics, and illness severity. Results: TEER comprised 89% of procedures. Black patients were younger (mean 62 vs 70 years) but presented with higher illness severity. After adjustment, Black patients had greater odds of receiving TEER (odds ratio (OR) = 1.36; 95% confidence interval (CI), 1.15-1.61). Mortality disparities persisted after adjustment: Black patients (OR = 1.49; 95% CI, 1.01-2.19; P = 0.045) and Asian/Pacific Islander patients OR = 2.20; 95% CI, 1.30-3.72; P = 0.003). Late presentation was more common among Black (24%) and Hispanic (27%) compared with White patients (13%). Conclusions: Black and Asian/Pacific Islander patients experience elevated inpatient mortality following mitral valve intervention that is not fully explained by covariates available in NIS. Late referral patterns are consistent with barriers to timely specialized care in minority populations.

Indexed as

Open mitral valve surgeryOutcomesProcedural selectionRacial differencesTEER

Identifiers

PMID42524426
PMCPMC13411771

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