Evidence map›Paper›PMID 42524409›Full record

ArticlePathogens & immunity2026

Mast Cells Control the Bacterial Burden and Grain Formation in Murine Experimental Actinomycetoma Induced by

Tomás Alejandro Suárez-Vázquez, Nallely López-López, Manuel Mejía-Torres, Adrián G Rosas-Taraco, Raquel Garza-Guajardo, Yatsiri G Meneses-Preza, Bibiana Patricia Ruiz-Sánchez, Rommel Chacón-Salinas, Mario César Salinas-Carmona

Abstract read
In one paragraph

Article in Pathogens & immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomás Alejandro Suárez-VázquezServicio de Inmunología, Universidad Autónoma de Nuevo León, Hospital Universitario Jose E. Gonzalez, Monterey, Nuevo León, Mexico.
Nallely López-LópezServicio de Inmunología, Universidad Autónoma de Nuevo León, Hospital Universitario Jose E. Gonzalez, Monterey, Nuevo León, Mexico.
Manuel Mejía-TorresServicio de Inmunología, Universidad Autónoma de Nuevo León, Hospital Universitario Jose E. Gonzalez, Monterey, Nuevo León, Mexico.
Adrián G Rosas-TaracoServicio de Inmunología, Universidad Autónoma de Nuevo León, Hospital Universitario Jose E. Gonzalez, Monterey, Nuevo León, Mexico.
Raquel Garza-GuajardoServicio de Patología, Universidad Autónoma de Nuevo León, Hospital Universitario José E. González, Monterrey, Nuevo León, Mexico.
Yatsiri G Meneses-PrezaDepartamento de Inmunología, Instituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Mexico.
Bibiana Patricia Ruiz-SánchezDepartamento de Inmunología, Instituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Mexico.
Rommel Chacón-SalinasDepartamento de Inmunología, Instituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Mexico.
Mario César Salinas-CarmonaServicio de Inmunología, Universidad Autónoma de Nuevo León, Hospital Universitario Jose E. Gonzalez, Monterey, Nuevo León, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The immunopathogenesis of actinomycetoma, a chronic granulomatous infection caused primarily by Methods: Using MCdeficient Results: MC-deficient mice exhibited a significant increase in bacterial load concomitant with attenuated late-phase (72-day) inflammation, characterized by reduced lesional neutrophilia and lymphocytic infiltration. Furthermore, MC absence disrupted the characteristic morphology of bacterial grains. Conclusions: These data demonstrate that MCs are directly activated by

Indexed as

ActinomycetomaChronic Bacterial InfectionMast CellsNocardia BrasiliensisWsh Mice

Identifiers

PMID42524409
PMCPMC13411753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.