ArticleSmart molecules : open access2026
Pyrene-linked heterocyclic pyrazoles: Synthesis, antimicrobial screening, and in silico molecular insights.
Article in Smart molecules : open access, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A library of structurally diverse pyrene-linked pyrazole derivatives was designed and synthesized, and their antimicrobial properties along with molecular interaction behavior were systematically investigated. The target compounds were efficiently prepared through a straightforward synthetic approach and fully characterized using standard spectroscopic techniques, confirming the formation of the desired heterocyclic framework. Biological evaluation against selected Gram-positive, Gram-negative, and fungal strains showed noticeable differences in activity across the series, indicating a strong dependence on the nature and position of substituents as well as their electronic characteristics. Notably, compound 4h emerged as the most active derivative, exhibiting significant antibacterial effects with inhibition zones of approximately 38 mm against
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.