Evidence map›Paper›PMID 42524179›Full record

ArticleBiotechnologia2026

Acne vaccine targeting

Indira Putri Negari, Azka Narari Khoerunnisa, Chun Ming Huang, Shinta Marito, Uuganbayar Gankhuyag, Mai Trinh Tang Nguyen, Aswin Rafif Khairullah, Cindy Mutiara Septani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biotechnologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Indira Putri NegariResearch Center for Vaccine and Drugs, National Research and Innovation Agency (BRIN), Bogor, West Java, Indonesia.
Azka Narari KhoerunnisaDepartment of Biology, Faculty of Military Mathematics and Natural Sciences, Universitas Pertahanan, Bogor, West Java, Indonesia.
Chun Ming HuangDepartment of Biomedical Sciences and Engineering, National Central University, Zhongli, Taoyuan, Taiwan.
Shinta MaritoDepartment of Pharmacy, Universitas Katolik Widya Mandala Surabaya, Surabaya, East Java, Indonesia.
Uuganbayar GankhuyagDepartment of Fundamental of Science, School of Nursing, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.
Mai Trinh Tang NguyenDepartment of Life Sciences, National Central University, Zhongli, Taoyuan, Taiwan.
Aswin Rafif KhairullahResearch Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, West Java, Indonesia.
Cindy Mutiara SeptaniResearch Center of Polymer Technology, National Research and Innovation Agency (BRIN), South Tangerang, Banten, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Limited attention paid to acne vulgaris has hindered progress in studying its pathological mechanisms and developing new treatments. While direct evidence confirming Materials and methods: Mass spectrometric analysis demonstrated that Results: Palmitic acid, a lipase-derived fatty acid, was identified as a major pro-inflammatory stimulus in sebocytes, confirming the central role of lipase in acne inflammation. Mice vaccinated with Conclusions: The

Indexed as

Cutibacterium acnesIL-6lipaseMIP-2palmitic acid

Identifiers

PMID42524179
PMCPMC13409370

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.