ArticleFrontiers in public health2026
Trust buffers price-related barriers to HPV vaccination among female college students: a cross-sectional study in China based on the 3C model.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: HPV vaccine hesitancy is prevalent among female college students in China, yet how trust interacts with cost concerns remains unclear. This study, grounded in the 3C model, examined whether trust in healthcare professionals buffers price-related barriers and identified high-risk subgroups. Methods: A cross-sectional survey recruited 4,326 female college students from 12 Chinese provinces. Trust, price perception, and vaccination intention were measured. Interaction effects were tested using the Breslow-Day test; a decision tree model (CART) identified high-risk profiles. Results: Trust in healthcare professionals showed the strongest positive correlation with vaccination intention ( Conclusion: Trust can buffer price-related barriers to HPV vaccination. Stratified interventions should prioritize the "low trust and high price" group through combined trust-building and financial support.
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