Evidence map›Paper›PMID 42523790›Full record

ArticleInternational journal of ophthalmology2026

Effect of active vision therapy on contrast sensitivity in bilateral amblyopia.

Saeed Rahmani, Saeedeh Hoseinmenni, Cirous Dehghani, Ebrahim Jafarzadehpour, Haleh Kangari, Jeffery Cooper, Mohammad Reza Talebnejad, Ali Reza Akbarzadeh Baghban, Enayatollah Osroosh

Abstract read
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Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Saeed RahmaniDepartment of Optometry, School of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences, Tehran 16169-13111, Iran.
Saeedeh HoseinmenniDepartment of Optometry, School of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences, Tehran 16169-13111, Iran.
Cirous DehghaniDiscipline of Optometry and Vision Science, University of Canberra, ACT 2617, Australia.
Ebrahim JafarzadehpourDepartment of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran 14496-14535, Iran.
Haleh KangariDepartment of Optometry, School of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences, Tehran 16169-13111, Iran.
Jeffery CooperSUNY College of Optometry, New York, NY 10036, USA.
Mohammad Reza TalebnejadPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz 71348-45794, Iran.
Ali Reza Akbarzadeh BaghbanProteomics Research Center, Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran 19716-53313, Iran.
Enayatollah OsrooshDepartment of Optometry, School of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences, Tehran 16169-13111, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the effectiveness of combining patching with active vision therapy, compared to patching with placebo training on contrast sensitivity (CS) in pediatric participants with bilateral refractive amblyopia.

methodsIn this double-blind, clinical trial, 43 participants aged 5-8 with bilateral refractive amblyopia, unresponsive to spectacles, were randomly assigned to either the experimental group (active vision therapy plus patching) or the control group (placebo treatment with patching) for four months. Active therapy included anti-suppression, accommodative, vergence, and visual memory exercises. CS was measured at baseline and after four months, serving as key outcome measures.

resultsForty participants (20 in each group) completed the study. The mean age for the experimental group (5 males) was 6.10±0.84y, and 6.50±1.15y for the control group (11 males). CS in the experimental group improved by 0.10 log (right eye), 0.14 log (left eye), and 0.07 log binocularly (

conclusionActive vision therapy leads to significant and accelerates improvements in CS among children with bilateral refractive amblyopia.

Indexed as

active vision therapybilateral refractive amblyopiachildrencontrast sensitivity

Identifiers

PMID42523790
PMCPMC13407463

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.