Evidence map›Paper›PMID 42523678›Full record

Articlenpj digital surgery2026

Prompt injection attacks on vision-language models for surgical decision support.

Zheyuan Zhang, Muhammad Ibtsaam Qadir, Matthias Carstens, Evan Hongyang Zhang, Madison Sarah Loiselle, Farren Marc Martinus, Maksymilian Ksawier Mroczkowski, Jan Clusmann, Jakob Nikolas Kather, Fiona R Kolbinger

Abstract read
In one paragraph

Article in npj digital surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Zheyuan ZhangWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN USA.
Muhammad Ibtsaam QadirWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN USA.
Matthias CarstensWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN USA.
Evan Hongyang ZhangWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN USA.
Madison Sarah LoiselleWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN USA.
Farren Marc MartinusWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN USA.
Maksymilian Ksawier MroczkowskiWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN USA.
Jan ClusmannElse Kroener Fresenius Center for Digital Health, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Jakob Nikolas KatherElse Kroener Fresenius Center for Digital Health, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.
Fiona R KolbingerWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN USA.

Funding

Indiana Clinical and Translational Sciences InstituteUM1TR004402 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI Sharon M Moe, Sarah Elizabeth Wiehe · 2023 to 2026
$21.6M
Integration of epidemiology, pathology, immunology and outcomes in colorectal cancerR01CA263318 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI STEPHEN B GRUBER · 2022 to 2026
$3.4M
NCATS NIH HHS UM1 TR004402NCI NIH HHS R01 CA263318
6 · The paper itself

Abstract

Vision-language models (VLMs) hold promise for video-based surgical decision support tasks due to their capabilities to understand complex temporospatial (video) data. However, the same multimodal interfaces that enable such capabilities also introduce new vulnerabilities to manipulations through embedded deceptive text or images (prompt injection attacks). We systematically evaluated four state-of-the-art VLMs using textual and temporally-varying visual prompt injection attacks across 100 curated surgical video clips spanning 8 clinically relevant surgical decision support tasks. While Gemini 2.5 Pro achieved the highest baseline accuracy (mean ± SD: 0.80 ± 0.01), all models suffered significant performance declines under attacks. GPT-o4-mini-high was most vulnerable (baseline accuracy: 0.65 ± 0.05; under prolonged visual attack: 0.24 ± 0.03,

Indexed as

DiseasesHealth careMedical research

Identifiers

PMID42523678
PMCPMC13407163

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.