ArticleResearch square2026
Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Background: Infections with Methods: Archived blood samples from patients from Argentina, Honduras and Mexico were stratified as confirmed positive or serodiscordant based on previous serological testing, and Results: A total of 532 mini-exon sequences were obtained (7.3 ± 0.5 haplotypes/individual), covering TcI, TcII, TcIV, TcV and TcVI DTUs, in similar proportions among countries, but variable proportions among individuals. Phylogenetic analysis indicated a significant geographic structuring of TcI, TcII, TcV and TcVI among countries, as well as clustering associated with discordant serology for TcI, TcII and TcV DTUs. Between 5-12 SNPs among these DTUs supported the association with discordant serology, and their frequency among countries mirrored that of serodiscordance. Conclusion: These results point to the cruziome and genetic differentiation within TcI, TcII and TcV DTUs to explain a large part of geographic differences in diagnostic performance. Thus, it is critical to account for the local diversity of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.