Evidence map›Paper›PMID 42523543›Full record

ArticleResearch square2026

Environmental determinants of Parkinson's disease and attributable burden in Latin America.

Daniel Teixeira-Dos-Santos, Henry Mauricio Chaparro-Solano, Juan Felipe Duarte-Zambrano, Thiago Leal, Miguel Inca-Martinez, Emily Waldo, Alastair Noyce, Dario Sergio Adamec, Emilia Mabel Gatto, Bruno Lopes Santos-Lobato and 51 more

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

61 authors.

Daniel Teixeira-Dos-SantosCleveland Clinic.
Henry Mauricio Chaparro-SolanoCase Western Reserve University.
Juan Felipe Duarte-ZambranoCleveland Clinic.
Thiago LealMorehouse School of Medicine.
Miguel Inca-MartinezCleveland Clinic.
Emily WaldoCleveland Clinic.
Alastair NoyceQueen Mary University of London.
Dario Sergio AdamecHospital Posadas.
Emilia Mabel GattoHospital de Niños de la Santísima Trinidad.
Bruno Lopes Santos-LobatoHospital Ophir Loyola.
Juliana Dos Santos DuarteUniversidade Federal do Pará.
Francisco Eduardo Costa CardosoUniversidade Federal de Minas Gerais.
Grace Helena LetroHospital PUC-Campinas.
Gonzalo ArboledaUniversidad Nacional de Colombia.
Jorge OrozcoFundación Valle del Lili.
Beatriz Muñoz OspinaIcesi University.
Paola Medina-CorderoFundación Valle del Lili.
Pedro Chana-CuevasUniversidad de Santiago de Chile.
Ximena Pizarro-CorreaCETRAM.
Philippe SallesCETRAM.
David AguillonUniversity of Antioquia.
David PinedaUniversity of Antioquia.
Susana Lissette Peña MartínezUniversidad Dr. Andrés Bello.
Tatiana AscencioUniversidad Dr. Andrés Bello.
Maria Valentina MüllerHospital de Clínicas "José de San Martín".
Marcelo MerelloFundación para la Lucha contra las Enfermedades Neurológicas de la Infancia.
Florencia Nicole WainbergFundación para la Lucha contra las Enfermedades Neurológicas de la Infancia.
Pedro Braga-NetoFederal University of Ceará.
Deborah RangelFederal University of Ceará.
Marcela Susana TelaHospital General de Agudos Dr. Juan A. Fernandez.
Evelin Álvarez-HerreraCentral American Technological University.
Mayela Rodríguez-ViolanteNational Institute of Neurology and Neurosurgery.
Amin Cervantes-ArriagaNational Institute of Neurological Sciences.
Daniel Martinez-RamirezHospital Angeles Valle Oriente.
Artur SchuhFederal University of Rio Grande do Sul.
Carlos RiederFederal University of Health Sciences of Porto Alegre.
Mario Cornejo-OlivasScientific University of the South.
Cintia ArmasNational Institute of Neurological Sciences.
Julia Rios-PintoUniversidad Peruana Los Andes.
Angel Medina-ColqueRegional Health Directorate of Puno.
Koni Mejia-RojasEDMECON Continuing Medical Education.
Angel ViñuelaManati Medical Center and Fundación Parkinson Puerto Rico.
Ana Lucia RossoHospital Universitário Clementino Fraga Filho.
Marcelo KauffmanHospital Ramos Mejía.
Vitor TumasRibeirão Preto Medical School, University of São Paulo.
Gabriel VilelaRibeirão Preto Medical School, University of São Paulo.
Vanderci BorgesFederal University of São Paulo.
Cesar AvilaNational Scientific and Technical Research Council and National University of Tucuman.
Patricio OlguínUniversity of Chile.
Alicia ColomboUniversity of Chile.
Juan Cristobal NuñezClínica Alemana Santiago and Hospital Clínico Universidad de Chile.
Samuel JorqueraUniversity of Chile.
Elias Fernandez-ToledoUniversity of Concepción.
Alejandra Lázaro-FigueroaNational Autonomous University of Mexico.
Juan Manuel Esquivias-FaríasNational Autonomous University of Mexico.
Ingrid Estrada-BellmannUniversity Hospital.
Paula Reyes-PérezUniversidad Nacional Autónoma de México.
Alejandra Medina-RiveraUniversidad Nacional Autónoma de México.
Sarael AlcauterNational Autonomous University of Mexico.
María Teresa Muñoz-QuezadaUniversity of Chile.
Ignacio MataCleveland Clinic.

Funding

Additional Sequencing for the Alzheimer Disease Sequencing Project (ADSP) the Follow-Up Study (FUS), The Global Population InitiativeU01AG076482 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Clifton L Dalgard, ANTHONY JOHN GRISWOLD · 2022 to 2026
$26.9M
Modeling the impact of Women's Specific Health Factors in PD outcomes in LatinasR01NS112499 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI FERNANDEZ MATA, IGNACIO · 2020 to 2024
$3.3M
Unraveling subcontinental ancestries across Africa, Americas and Europe, and implications for admixture/association mapping of complex traitsR00HG012211 · NHGRI · MOREHOUSE SCHOOL OF MEDICINE · PI Mateus Henrique Gouveia · 2025 to 2026
$498k
BLRD VA I01 BX005978NHGRI NIH HHS R00 HG012211NIA NIH HHS U01 AG076482NINDS NIH HHS R01 NS112499
6 · The paper itself

Abstract

We investigated environmental determinants of Parkinson's disease (PD) and their attributable burden in a case-control study of 9,887 participants from nine Latin American countries. Logistic regression adjusted for age, sex, and country estimated associations, and population attributable fractions (PAFs) were calculated for modifiable risk factors. Weekly caffeine consumption (adjusted odds ratio [aOR] 0.77,

Identifiers

PMID42523543
PMCPMC13405441

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.