Evidence map›Paper›PMID 42523465›Full record

ArticleResearch square2026

Clinical, cellular, and genomic consequences of a population-enriched

Robert Lease, Rediet T Oshone, Yumna Ahmed, Samaneh Ali, Sterling Arjona, Jayme Choe, Carlo Colantuoni, Marcia Cortes-Gutierrez, Brian R Herb, Elizabeth M Humphries and 20 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Robert LeaseInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Rediet T OshoneInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Yumna AhmedInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Samaneh AliInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Sterling ArjonaInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Jayme ChoeInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Carlo ColantuoniInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Marcia Cortes-GutierrezInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Brian R HerbInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Elizabeth M HumphriesInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Evelina MocciInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Rowan O'Hara-PayneInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
Ryan KuehnerLancaster Bible College, Lancaster, PA, USA.
Coleen DamcottDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Hemalatha SampathDepartment of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Susan ShaubProgram in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Kamah WoelfelProgram in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Charlene WolfordProgram in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Kwangmi AhnHuman Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USA.
Sevilla Detera-WadleighHuman Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USA.
Sander MarkxDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.
Joseph A GogosDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.
Peter KochunovDepartment of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Toni I PollinDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Teodor PostolacheDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Alan R ShuldinerDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Francis J McMahonHuman Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USA.
L Elliot HongDepartment of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Braxton D MitchellDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Seth A AmentInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.

Funding

Mapping genes that contribute to bipolar disorderZIAMH002810 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MCMAHON, FRANCIS J · 2009 to 2025
$31.2M
Amish Connectome Project on Mental IllnessU01MH108148 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT, KOCHUNOV, PETER V. · 2015 to 2018
$4.3M
Multi-scale consequences of variants in the schizophrenia risk gene SETD1A in a population isolate.R01MH129343 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI Seth Abrams Ament · 2022 to 2026
$1.9M
Lifespan Vascular Biology on White MatterR01NS114628 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT, KOCHUNOV, PETER V. · 2024 to 2024
$770k
Intramural NIH HHS ZIA MH002810NIMH NIH HHS R01 MH129343NIMH NIH HHS U01 MH108148NINDS NIH HHS R01 NS114628
6 · The paper itself

Abstract

Rare variants in

Identifiers

PMID42523465
PMCPMC13405502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.