Evidence map›Paper›PMID 42523432›Full record

ArticlebioRxiv : the preprint server for biology2026

Endogenous autophagosome reporters reveal redundant and non-redundant roles of LGG-1 and LGG-2 in

Heather Tsong, Mya Rodriguez, Andrea K H Stavoe

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Heather TsongDepartment of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Houston, TX, USA.
Mya RodriguezDepartment of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Houston, TX, USA.
Andrea K H StavoeDepartment of Neurobiology and Anatomy, University of Texas Health Science Center at Houston, Houston, TX, USA.ORCID 0000-0002-4073-4565

Funding

Tissue-Specific Regulation of Autophagy by PROPPINsR35GM159826 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ANDREA STAVOE · 2025 to 2026
$780k
WIPI2B/ATG-18 phosphorylation regulates neuronal autophagosome biogenesis in vivoF31AG086033 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Heather Tsong · 2024 to 2026
$75k
NIA NIH HHS F31 AG086033NIGMS NIH HHS R35 GM159826
6 · The paper itself

Abstract

Autophagy is a conserved cellular recycling pathway essential for neuronal development and homeostasis. Neurons are highly polarized cells that rely on the continual turnover of cytoplasmic content through processes like autophagy to maintain cellular function. Here, we employed novel endogenous autophagosome reporters to define the distinct expression patterns, spatial distribution, and compensatory potential of the two

Identifiers

PMID42523432
PMCPMC13405388

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.