Evidence map›Paper›PMID 42523411›Full record

ArticlebioRxiv : the preprint server for biology2026

Quorum sensing underlies the establishment and maintenance of marginal zone B cells.

Apoorva Singh, Melissa Verheijen, Thea Hogan, Andrew J Yates, Benedict Seddon, Sanket Rane

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Apoorva SinghIrving Institute for Cancer Dynamics, Columbia University, New York, NY, USA.
Melissa VerheijenDepartment of Immunology, University College London, London, UK.
Thea HoganDepartment of Immunology, University College London, London, UK.
Andrew J YatesDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0003-4606-4483
Benedict SeddonDepartment of Immunology, University College London, London, UK.ORCID 0000-0003-4352-3373
Sanket RaneIrving Institute for Cancer Dynamics, Columbia University, New York, NY, USA.ORCID 0000-0003-2612-4725

Funding

Modeling the development, structure and regulation of T cell memoryR01AI093870 · NIAID · UNIVERSITY OF GLASGOW · PI YATES, ANDREW · 2011 to 2025
$5.9M
Integrative approaches defining the ontogeny, maintenance, and immune response dynamics of marginal-zone B cellsR01AI170965 · NIAID · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Sanket Rane · 2023 to 2026
$2.0M
NIAID NIH HHS R01 AI093870NIAID NIH HHS R01 AI170965
6 · The paper itself

Abstract

The marginal zone (MZ) of the spleen harbors B cells that play an indispensable role in immune defense, orchestrating rapid responses to blood-borne pathogens. Under steady-state conditions, MZ B cell numbers are maintained through the balance of

Indexed as

B cellsMathematical ModelingPopulation Dynamics

Identifiers

PMID42523411
PMCPMC13405276

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.