Evidence map›Paper›PMID 42523387›Full record

ArticlebioRxiv : the preprint server for biology2026

Conserved Transcriptomic Signatures of Sirt6 Activity: A Cross-Species RNA-seq Meta-analysis.

Arjun Khanna, Roja Sharma, Samira Xhaferi, Ullas Kolthur-Seetharam, Peng Jiang, Jackson Taylor

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arjun KhannaCenter for Gene Regulation in Health and Disease, Department of Biological, Geological and Environmental Sciences, Cleveland State University.ORCID 0009-0001-9142-345X
Roja SharmaCenter for Gene Regulation in Health and Disease, Department of Biological, Geological and Environmental Sciences, Cleveland State University.ORCID 0009-0002-1015-7266
Samira XhaferiCenter for Gene Regulation in Health and Disease, Department of Biological, Geological and Environmental Sciences, Cleveland State University.
Ullas Kolthur-SeetharamDepartment of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, India.ORCID 0000-0003-2612-1743
Peng JiangCenter for Gene Regulation in Health and Disease, Department of Biological, Geological and Environmental Sciences, Cleveland State University.ORCID 0000-0002-6057-7624
Jackson TaylorCenter for Gene Regulation in Health and Disease, Department of Biological, Geological and Environmental Sciences, Cleveland State University.ORCID 0000-0003-0382-6716

Funding

Somatic Activation of Retrotransposition: A New Molecular Mechanism of Aging?P01AG051449 · NIA · BROWN UNIVERSITY · PI John M Sedivy · 2016 to 2026
$30.4M
Mechanisms of Lifespan Regulation by Sirt6 in Drosophila melanogasterR00AG057812 · NIA · CLEVELAND STATE UNIVERSITY · PI TAYLOR, JACKSON RICHARD · 2023 to 2025
$733k
NIA NIH HHS P01 AG051449NIA NIH HHS R00 AG057812
6 · The paper itself

Abstract

The NAD

Identifiers

PMID42523387
PMCPMC13405160

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.