In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
24 authors.
Lucia ChenTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0009-0008-8748-3602 Kaiden ThompsonTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0009-0005-3204-4969 Muntasir KamalTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-5354-5747 Kateryna SihutaTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0009-0002-9150-6746 Irini TopalidouBasic Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washinton, United States of America.ORCID 0000-0003-1115-4251 Andrew R BurnsTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-8966-1280 Nazli H FarshourTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
Brittany CookeTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-6386-1655 Jessica KnoxTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-1465-5852 Yanqing JiangTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
Modhar Al QasserTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
Ermira ShuteriqiTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
Matej UsajTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-0675-2847 Justin ChingDepartment of Chemistry, Davenport Research Laboratories, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-2511-216X Arthur FlagetDepartment of Chemistry, Davenport Research Laboratories, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-8757-8304 Michael CostanzoTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-7906-2604 Guihong TanTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0001-7334-1154 Jessica LacosteTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-7222-4957 Mark LautensDepartment of Chemistry, Davenport Research Laboratories, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-0179-2914 Brenda AndrewsTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
Charles BooneTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-3542-6760 Mikko TaipaleTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-3811-1761 Nicolas J LehrbachBasic Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washinton, United States of America.ORCID 0000-0001-7342-4136 Peter J RoyTerrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-2959-2276 Funding
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5MNIH HHS P40 OD010440
6 · The paper itselfAbstract
Tioxazafen is an effective nematicide whose commercialization was halted because handlers reportedly developed rashes after working with seeds coated with a tioxazafen-laced cocktail. Here, we show that tioxazafen is bioactivated into toxic products by nematode and human cytochrome P450s. Through systematic analyses, we found that bioactivated tioxazafen disrupts proteasome function, leading to the accumulation of the NRF1 transcription factor ortholog SKN-1A in the nematode
Identifiers
PMID42523351
PMCPMC13405185
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390