Evidence map›Paper›PMID 42523324›Full record

ArticlebioRxiv : the preprint server for biology2026

Experimental evolution and functional genetics identify KIC1 as a determinant of reduced artemisinin susceptibility in Bangladeshi

Maisha Khair Nima, Nirjhar Bhattacharyya, Saiful Arefeen Sazed, Ching Swe Phru, Mohammad Shafiul Alam, Michael T Ferdig, Angana Mukherjee

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maisha Khair NimaDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Nirjhar BhattacharyyaDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Saiful Arefeen SazedInfectious Diseases Division, International Centre for Diarrheal Diseases Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Ching Swe PhruInfectious Diseases Division, International Centre for Diarrheal Diseases Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Mohammad Shafiul AlamInfectious Diseases Division, International Centre for Diarrheal Diseases Research, Bangladesh (icddr,b), Dhaka, Bangladesh.ORCID 0000-0001-8330-5499
Michael T FerdigDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Angana MukherjeeDepartment of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.ORCID 0000-0002-7080-494X

Funding

Deciphering P. falciparum artemisinin resistance in Bangladesh: a genotypic-phenotypic evaluation of Kelch13 dependent and independent determinantsR21AI180663 · NIAID · UNIVERSITY OF NOTRE DAME · PI MUKHERJEE, ANGANA · 2024 to 2025
$430k
NIAID NIH HHS R21 AI180663
6 · The paper itself

Abstract

Bangladesh has greatly reduced malaria transmission, but persistent

Indexed as

artemisinin resistanceBangladeshChittagong Hill Tractsdihydroartemisininelastic netexperimental evolutionKIC1Plasmodium falciparumrare-variant gene-score analysisring-stage survival assay

Identifiers

PMID42523324
PMCPMC13405019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.