Evidence map›Paper›PMID 42523224›Full record

ArticlebioRxiv : the preprint server for biology2026

Bacterial-driven development is mediated by Calcium-Dependent Intrinsic Apoptosis in the Squid-Vibrio Symbiosis.

Madison Emery, Alice Breaux Walker, Bethany Elizabeth Rader, Elizabeth Anne Chapman Heath-Heckman

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Madison EmeryDepartment of Microbiology, Genetics, and Immunology, Michigan State University.ORCID 0009-0000-2590-1110
Alice Breaux WalkerDepartment of Microbiology, Genetics, and Immunology, Michigan State University.ORCID 0009-0006-3638-0385
Bethany Elizabeth RaderDepartment of Microbiology, Southern Illinois University.
Elizabeth Anne Chapman Heath-HeckmanDepartment of Microbiology, Genetics, and Immunology, Michigan State University.

Funding

Elucidating Molecular Mechanisms Underlying Cooperation in Animal-Bacterial SymbiosesR35GM150478 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Elizabeth A. Heath-Heckman · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM150478
6 · The paper itself

Abstract

The presence of beneficial microbes serves as a post-embryonic developmental cue in a wide array of metazoan species. However, the mechanisms through which mutualistic bacteria induce developmental processes such as apoptosis are poorly understood. A leading model system utilized to study bacteria-induced developmental apoptosis is the Hawaiian bobtail squid,

Identifiers

PMID42523224
PMCPMC13404735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.