In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
23 authors.
Magnus S BauerDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-1357-2852 Dongyang LiDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Kody A KluptDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada K7L3N6.ORCID 0000-0003-0720-2310 Matthias GlöglDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-7011-8184 Ana María Fernández EscamillaInstitute for Research in Biotechnology and Health (IDiBE), Miguel Hernandez University, 03202 Elche, Alicante, Spain.
Thomas SchlichthaerleProfessorship of AI-Guided Protein Design, Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, Garching, Germany.ORCID 0000-0003-4444-2575 Edin MuratspahićDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-6011-0805 Xinru WangDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Center for Drug Discovery, Bouve College of Health Sciences, Northeastern University, Boston, MA.ORCID 0000-0001-5994-707X Ludwig SchmidererDivision of Molecular Medicine and Gene Therapy, Department of Laboratory Medicine and Lund Stem Cell Center, Lund University, 221 00 Lund, Sweden.ORCID 0000-0003-3569-7699 Sebastian KennyDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-3541-2577 Brian CoventryDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-6910-6255 Bulat FaezovDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-8656-4872 Wei ChenDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-5255-4166 Alex F ShidaDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.
Gyu Rie LeeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.ORCID 0000-0002-9119-5303 Yang HsiaDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-7467-8373 Ryan D KiblerDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-6984-9887 Michael B ElowitzDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0002-1221-0967 Daniel LiethaMolecular and Cellular Biosciences, Margarita Salas Center for Biological Research, Spanish National Research Council, Madrid 28040, Spain.ORCID 0000-0002-6133-6486 Behnam NabetHuman Biology Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-6738-4200 David BakerDepartment of Biochemistry, University of Washington, Seattle, WA 98195, USA; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-7896-6217 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Protein kinases are critical regulators of cellular signaling, but precise modulation of their activity remains challenging due to their high structural conservation. Here, we present
Identifiers
PMID42523218
PMCPMC13404887
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