Evidence map›Paper›PMID 42523152›Full record

Observational studyJournal of Alzheimer's disease : JAD2026

Exploring the relationship between Alzheimer's disease and lower extremity isokinetic muscle strength in community-dwelling older adults: A cross-sectional observational study.

Marcos Paulo Braz De Oliveira, Silvia Lanziotti Azevedo Da Silva, Natália Oiring De Castro Cezar, Carla Rigo Lima-Truax, Brendon David Truax, Sónia Brito-Costa, Anielle Cristhine De Medeiros Takahashi, Paula Regina Mendes Da Silva Serrão, Larissa Pires De Andrade

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcos Paulo Braz De OliveiraPhysical Therapy Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
Silvia Lanziotti Azevedo Da SilvaCollective Health Department, Federal University of Juiz de Fora, Juiz de Fora, Brazil.
Natália Oiring De Castro CezarMedicine Department, State University of Minas Gerais, Passos, Brazil.ORCID 0000-0002-8264-3565
Carla Rigo Lima-TruaxPhysical Therapy Department, The University of Alabama at Birmingham, Birmingham, AL, USA.
Brendon David TruaxMedicine Department, The University of Alabama at Birmingham, Birmingham, AL, USA.
Sónia Brito-CostaCentre for Research and Innovation in Education (inED), Polytechnic University of Coimbra, Coimbra, Portugal.ORCID 0000-0002-7074-887X
Anielle Cristhine De Medeiros TakahashiPhysical Therapy Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
Paula Regina Mendes Da Silva SerrãoPhysical Therapy Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
Larissa Pires De AndradePhysical Therapy Department, Federal University of São Carlos, São Carlos, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundOlder adults diagnosed with Alzheimer's disease (AD) often experience diminished muscle strength, highlighting the continued importance of evaluating muscle function in this population.ObjectiveTo examine the relationship between AD and isokinetic lower limb muscle strength in older adults.MethodsA cross-sectional observational study was conducted to examine the association between AD and lower limb isokinetic muscle strength in community-dwelling older adults. AD diagnosis was the independent variable; dependent variables included peak torque, average peak torque, and total work. A standardized isokinetic protocol adapted for older adults with cognitive impairment was used to assess knee (flexion/extension at 60°/s and 180°/s) and ankle (dorsiflexion/plantar flexion at 30°/s) strength. Crude and adjusted linear regression models evaluated statistical associations, with significance set at

Indexed as

Alzheimer DiseaseLower ExtremityMuscle StrengthAgedAged, 80 and overAging in PlaceCross-Sectional StudiesFemaleHumansIndependent LivingMaleMuscle, SkeletalTorqueagedAlzheimer's diseasedementiaisokinetic dynamometrymuscle strength

Identifiers

PMID42523152
PMCPMC13688339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.