Observational studyPaediatric anaesthesia2026
Incidence, Predictors, and Outcomes of Early Postoperative Dysnatremia After Pediatric Neurosurgery: A Prospective Observational Study.
Observational study in Paediatric anaesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Incidence, Predictors, and Outcomes of Early Postoperative Dysnatremia After Pediatric Neurosurgery: A Prospective Observational Study.Paediatric anaesthesia · 2026Observational
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSodium abnormalities are frequent in the neuro intensive care unit (ICU) settings. Dysnatremia can also manifest in the perioperative period in neurosurgical patients and can lead to adverse consequences. The burden of dysnatremia following elective pediatric neurosurgery is unclear. Hence, we aimed to assess the incidence, risk factors, and outcomes of dysnatremia in children undergoing elective neurosurgeries.
methodsThis was a single-center, prospective observational study in consecutive elective pediatric neurosurgical patients aged < 18 years. Perioperative data were collected for the first 3 postoperative days and included age, gender, weight, American Society of Anesthesiologists Physical Status classification, location of surgical pathology, preoperative sodium, intraoperative blood loss and transfusion, intraoperative fluid balance, balanced salt solution use, perioperative vomiting, steroid use, seizures, Glasgow coma scale score, duration of ICU and hospital stay, and in-hospital mortality. Hyponatremia was defined as serum sodium < 135 mEq/L, hypernatremia as serum sodium > 145 mEq/L, and dysnatremia as the presence of either hyponatremia or hypernatremia.
resultsSix hundred sixty-eight children who underwent neurosurgery had perioperative sodium values assessed during the 22-month study period. The incidence of postoperative dysnatremia was 18.6% (124/668). In multivariate regression analysis, sellar/suprasellar region pathologies, preoperative dysnatremia, and higher blood loss were predictors of postoperative dysnatremia. Children with postoperative dysnatremia had a higher occurrence of seizures, neurological deterioration, and death, and longer ICU and hospital stays.
conclusionsAbout one-in-five children undergoing neurosurgery develop postoperative dysnatremia, and it is predicted by preoperative dysnatremia, sellar/suprasellar pathology, and higher blood loss. Dysnatremia is associated with poor clinical outcomes. STUDY REGISTRATION: Clinical Trials Registry-India: CTRI/2022/01/039795.
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