ArticleJournal of biophotonics2026
Influence of Sample Preparation Methods for Porcine Tissue: Calibration-Free LIBS for In Vivo Applications.
Article in Journal of biophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Calibration-free laser-induced breakdown spectroscopy (CF-LIBS) has the advantage of eliminating the need for complex sample preparation. This study investigates the impact of various preparation techniques on porcine tissue. These methods include embedding the tissue in PBS or deionised water, and analysing untreated tissue or tissue that has been cut using liquid nitrogen. The results demonstrate that embedding samples does result in changes to the LIBS spectra. Minor deviations in the magnesium and sodium intensity ratios were observed in the skin. However, it should be noted that embedded samples may exhibit altered elemental signatures due to ionic exchange with the immersion medium, despite facilitating sample handling. It is important to note that the immediate measurement of untreated samples is critical, as post-mortem changes can lead to shifts in elemental concentrations. These findings show that CF-LIBS can be reliably performed on untreated biological samples, thus supporting its use in vivo diagnostics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.