Evidence map›Paper›PMID 42522290›Full record

Trial reportMolecular nutrition & food research2026

Effect of Chitosan Supplementation and Lifestyle Changes on Health and Gut Microbiota in Icelandic Females With Obesity.

Thelma Rún Rúnarsdóttir, Sigurlaug Skírnisdóttir, Hildur Thors, Hjördís Harðardóttir, Karla F Corral-Jara, Alexandra M Klonowski, Þórhallur Ingi Halldórsson, Marta Guðjónsdóttir

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Molecular nutrition & food research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04551365 (Effects of Lifestyle Changes and Chitosan on Gut Microbiota Modulation, Body Weight and Important Health Markers in Selected Population Groups), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04551365 nacompletednot on this map

Effects of Lifestyle Changes and Chitosan on Gut Microbiota Modulation, Body Weight and Important Health Markers in Selected Population Groups: A Double-blind, Block-randomized, Placebo-controlled Study

TypeinterventionalSponsorUniversity of IcelandRan2020 to 2024Enrolled106ConditionsObesity, LifestyleArmsLifestyle changes, Chitosan, Placebo
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thelma Rún RúnarsdóttirFaculty of Food Science and Nutrition, School of Health Sciences, University of Iceland, Reykjavík, Iceland.
Sigurlaug SkírnisdóttirMatis Ltd., Reykjavík, Iceland.
Hildur ThorsReykjalundur Rehabilitation Center, Mosfellsbær, Iceland.
Hjördís HarðardóttirReykjalundur Rehabilitation Center, Mosfellsbær, Iceland.
Karla F Corral-JaraMatis Ltd., Reykjavík, Iceland.
Alexandra M KlonowskiMatis Ltd., Reykjavík, Iceland.
Þórhallur Ingi HalldórssonFaculty of Food Science and Nutrition, School of Health Sciences, University of Iceland, Reykjavík, Iceland.
Marta GuðjónsdóttirFaculty of Medicine, School of Health Sciences, University of Iceland, Reykjavík, Iceland.

Funding

Technology Development Fund in Iceland 198694-0611
6 · The paper itself

Abstract

Evaluate the effect of chitosan supplementation with structured lifestyle changes on health factors and gut microbiota in females with obesity following an interdisciplinary rehabilitation program. In this randomized, double-blind, placebo-controlled trial (NCT04551365), 33 Icelandic females with obesity (BMI 30.0-54.1 kg/m

Indexed as

ChitosanDietary SupplementsGastrointestinal MicrobiomeLife StyleObesityAdultBody CompositionBody Mass IndexDouble-Blind MethodFemaleHumansIcelandMiddle AgedChitosanchitosan supplementationgut microbiotahealth factorsobesityrandomized clinical trial

Identifiers

PMID42522290
PMCPMC13416228

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.