Evidence map›Paper›PMID 42522221›Full record

ArticlePsychological medicine2026

Developmental trajectories of sleep in offspring of parents with mood disorders.

Zachary Hubshman, Anna Nazarova, Mayank Ramchandani, Jason d'Eon, Nitya Adepalli, Kathryn Freeman, Max Wang, Ryan E R Reid, Barbara Pavlova, Rudolf Uher

Abstract read
In one paragraph

Article in Psychological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zachary HubshmanDalhousie University, Canada.ORCID 0009-0000-9101-8107
Anna NazarovaNova Scotia Health Authority, Canada.ORCID 0009-0009-4972-2585
Mayank RamchandaniDalhousie University, Canada.
Jason d'EonDalhousie University, Canada.
Nitya AdepalliNova Scotia Health Authority, Canada.ORCID 0009-0004-6852-5046
Kathryn FreemanDalhousie University, Canada.ORCID 0000-0002-7329-3348
Max WangNova Scotia Health Authority, Canada.ORCID 0009-0007-3199-7041
Ryan E R ReidSt Francis Xavier University, Canada.ORCID 0000-0002-8573-1413
Barbara PavlovaDalhousie University, Canada.
Rudolf UherDalhousie University, Canada.

Funding

Canada Research Chairs 950 - 233141CIHR 169025, 178222, 197778, 148394
6 · The paper itself

Abstract

backgroundYouth at familial risk for mood disorders often report disturbed sleep, yet it is unclear which aspects of sleep distinguish them from low-risk peers or when differences emerge developmentally.

methodsA total of 176 youth at familial risk for mood disorders (mean age = 14.6 years) and 119 control youth (mean age = 13.8 years), aged 8 to 25, wore wrist actigraphy continuously for 2 weeks. Total sleep time, sleep midpoint timing, and sleep regularity were derived from actigraphy data. Generalized additive mixed models estimated nonlinear developmental trajectories across age. Confidence bands identified age intervals at which groups diverged.

resultsHigh- and low-risk youth followed different developmental patterns of total sleep time (

conclusionsHigh-risk youth showed poorer sleep than controls in early adolescence but better sleep in late adolescence through young adulthood, possibly reflecting shifting sleep priorities across development, though the mechanisms underlying these differences remain unclear.

Indexed as

Child of Impaired ParentsMood DisordersSleepSleep Wake DisordersActigraphyAdolescentAdultChildFemaleHumansMaleSleep DurationYoung Adultactigraphycohortdevelopmentfamilial riskmood disorderssleep

Identifiers

PMID42522221
PMCPMC13439250

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