ArticleHuman vaccines & immunotherapeutics2026
Psychosocial factors influencing HPV vaccination intention among male college students in Hangzhou city: A cross-sectional study based on an extended theory of planned behavior model.
Article in Human vaccines & immunotherapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Human papillomavirus (HPV) vaccination for males is critical for reducing the global burden of HPV-related diseases. This study utilized an extended Theory of Planned Behavior (TPB) framework to identify determinants of vaccination intentions among Chinese male undergraduate students. A cross-sectional study was conducted between March and May 2025 in Hangzhou, China, recruiting 1,310 participants via multi-stage stratified cluster sampling. The dependent variable was vaccination intention. Independent variables included sociodemographics, TPB constructs (behavior attitude [BA], subjective norms [SN], and perceived behavioral control [PBC]), HPV knowledge and risk perception. We employed a three-step hierarchical linear model (Model 1: sociodemographics; Model 2: adding TPB constructs; Model 3: adding HPV knowledge/risk) and structural equation modeling (SEM) to test latent paths. Among the 1,310 participants (balanced across four academic years), 62.7% expressed a willingness to receive the HPV vaccine. Hierarchical regression revealed that sociodemographics explained 2.1% of the variance in vaccination intention (Model 1), which increased to 25.1% with the inclusion of TPB constructs (Model 2), and reached 32.7% in the final model (Model 3) (F = 126.245,
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