Evidence map›Paper›PMID 42521859›Full record

ReviewPflugers Archiv : European journal of physiology2026

The bile acid-sensive ion channel (BASIC) is expressed in pancreatic α-cells and involved in glucagon secretion.

Jingyu Yang, Stefan Gründer, Dominik Wiemuth

Abstract readReview
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jingyu YangInstitute of Physiology, RWTH Aachen University, D-52074, Aachen, Germany.ORCID http://orcid.org/0009-0009-0866-5692
Stefan GründerInstitute of Physiology, RWTH Aachen University, D-52074, Aachen, Germany.ORCID http://orcid.org/0000-0002-7635-9883
Dominik WiemuthInstitute of Physiology, RWTH Aachen University, D-52074, Aachen, Germany. dwiemuth@ukaachen.de.ORCID http://orcid.org/0000-0002-0563-4198

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic α-cells play a key role in glucose homeostasis through glucagon secretion. Here, we discover that the bile acid-sensitive ion channel (BASIC), a Na

Indexed as

Epithelial Sodium ChannelsGlucagonGlucagon-Secreting CellsAnimalsBile Acids and SaltsMiceMice, Inbred C57BLBile Acids and SaltsEpithelial Sodium ChannelsGlucagonBile acid-sensitive ion channel (BASIC)DEG/ENaCGlucagonPancreatic α-cell

Identifiers

PMID42521859
PMCPMC13415342

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.