Evidence map›Paper›PMID 42521829›Full record

ArticleSurgical endoscopy2026

Prospective multicenter validation of a clinical score model for muscular injury risk stratification during esophageal endoscopic submucosal dissection.

Zi-Han Geng, Peng Lyu, Lu Yao, Yi-Fan Qu, Yan Zhu, Pei-Yao Fu, Wei-Feng Chen, Ping-Hong Zhou, Quan-Lin Li, Zu-Qiang Liu

Abstract readMulticenter StudyValidation Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zi-Han Geng *Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China.
Peng Lyu *Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
Lu Yao *Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China.
Yi-Fan QuEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China.
Yan ZhuEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China.
Pei-Yao FuEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China.
Wei-Feng ChenEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China.
Ping-Hong ZhouEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China. zhou.pinghong@zs-hospital.sh.cn.ORCID http://orcid.org/0000-0002-5434-0540
Quan-Lin LiEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China. li.quanlin@zs-hospital.sh.cn.
Zu-Qiang LiuEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China. liu.zuqiang@zs-hospital.sh.cn.

Funding

National Natural Science Foundation of China 82170555National Natural Science Foundation of China 82200600National Natural Science Foundation of China 82270569Shanghai Academic/Technology Research Leader 22XD1422400Shanghai Rising Stars of Medical Talent Youth Development Program 20224Z0005Shuguang Program of Shanghai Education Development Foundation and Shanghai Municipal Education Commission 22SG06the 74th General Support of China Postdoctoral Science Foundation 2023M740675
6 · The paper itself

Abstract

BACKGROUND AND

aimsA clinical score model has been developed to stratify the risk of muscular injury during esophageal endoscopic submucosal dissection (ESD). This study aimed to prospectively validate the model in a multicenter cohort.

methodsA multicenter prospective cohort analysis of esophageal ESD was conducted. Individual data on patients, lesions, and outcomes of ESD were utilized to validate the model for muscular injury risk stratification.

resultsA total of 704 patients with esophageal lesions treated by ESD across two hospitals were included in the study. Muscular injury occurred in 10.5% of low-risk and 61.5% of high-risk patients. The scoring system demonstrated good discriminatory performance, with an AUC of 0.761 (95% CI 0.713-0.809).

conclusionsThe clinical score model showed acceptable performance for muscular injury risk stratification during esophageal ESD and may support perioperative decision-making.

Indexed as

Endoscopic Mucosal ResectionEsophageal NeoplasmsEsophagoscopyEsophagusIntraoperative ComplicationsMuscle, SmoothAgedFemaleHumansMaleMiddle AgedProspective StudiesRisk AssessmentClinical score modelEndoscopic submucosal dissection (ESD)Muscular injuryProspective validationRisk stratification

Identifiers

PMID42521829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.