Evidence map›Paper›PMID 42521660›Full record

ArticleEmerging infectious diseases2026

Detection of Congenital Syphilis via Digital PCR and Next-Generation Sequencing, Colombia.

Ana M Bossa-Castro, Narda M Olarte Escobar, Ismael Alberto Valderrama Márquez, Deisy Abril, Luis Fuentes, Zayda Lorena Corredor-Rozo, Ruth Liliana López Cruz, Sharon Hassbleidy Ochoa Ramírez, José Alejandro Mojica Madera, Pedro José Ramos Cabrera and 5 more

Abstract readCase Reports
In one paragraph

Article in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ana M Bossa-Castro
Narda M Olarte Escobar
Ismael Alberto Valderrama Márquez
Deisy Abril
Luis Fuentes
Zayda Lorena Corredor-Rozo
Ruth Liliana López Cruz
Sharon Hassbleidy Ochoa Ramírez
José Alejandro Mojica Madera
Pedro José Ramos Cabrera
Jorge Eliecer Castellanos Corredor
Nidia Aydee Garay Bernal
Ana María Gómez Puentes
Carlos Alberto Morales Pertuz
Javier Escobar-Pérez

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe congenital syphilis in a newborn whose mother had secondary syphilis diagnosed during pregnancy and received a single penicillin dose. Molecular methods detected an extremely low Treponema pallidum load in the mother but higher load in the neonate. Our findings support using molecular methods for detecting vertical T. pallidum transmission.

Indexed as

High-Throughput Nucleotide SequencingPolymerase Chain ReactionSyphilis, CongenitalTreponema pallidumColombiaFemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousbacteriaColombiacongenital syphilisdigital PCRnext-generation sequencingSyphilisTreponema pallidum

Identifiers

PMID42521660
PMCPMC13426889

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.