Evidence map›Paper›PMID 42521499›Full record

ArticleOccupational and environmental medicine2026

Change in physical workload and the risk of work disability due to musculoskeletal disorders: a register-based study of 1 703 935 workers in Sweden.

Daniel Falkstedt, Tomas Hemmingsson, Laura Punnett, Katarina Kjellberg, Alicia Kurowski, Kuan-Yu Pan, Melody Almroth

Abstract read
In one paragraph

Article in Occupational and environmental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel FalkstedtInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-4441-7003
Tomas HemmingssonInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Laura PunnettDepartment of Biomedical Engineering, University of Massachusetts, Lowell, Massachusetts, USA.
Katarina KjellbergInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-0458-6243
Alicia KurowskiDepartment of Biomedical Engineering, University of Massachusetts, Lowell, Massachusetts, USA.
Kuan-Yu PanInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-0523-663X
Melody AlmrothInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden melody.almroth@ki.se.ORCID http://orcid.org/0000-0002-4167-9174

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis register-based study examined whether changes over 14 years in occupational physical workload (PWL) affected the risk of registered work disability due to a musculoskeletal disorder (MSD).

methodsThis study included 1 703 935 workers in Sweden in 2005. PWL exposure was measured using job-exposure matrices linked to registered occupations in 1990 and 2005; change in PWL was defined between categories (low, medium, high) in either direction. The outcome was cumulative incidence of 'work disability' (either long-term sickness of at least 2 years or disability pension) due to MSD from 2006 to 2019. Crude and multivariate Cox proportional hazards regression models estimated sex-specific HRs with 95% CIs. Models were adjusted for sociodemographic factors and health and employment history.

resultsA total of 33 369 individuals (1.96%) became work disability cases during follow-up. Compared with workers with consistently high PWL, any reduction in PWL was associated with a decreased risk of work disability due to MSD (women: HR 0.57, 95% CI 0.52 to 0.63, men: HR 0.59, 95% CI 0.52 to 0.66 for change from high to low exposure). Compared with workers with consistently low PWL, any increase was associated with a higher risk of work disability due to MSD (women: HR 1.68, 95% CI 1.53 to 1.86, men: HR 2.19, 95% CI 1.89 to 2.52 for change from low to high).

conclusionIn both sexes, decreases in PWL exposure were associated with a lower risk of MSD disability and increases in exposure with a higher risk.

Indexed as

Musculoskeletal DiseasesOccupational DiseasesPersons with DisabilitiesWorkloadAdultFemaleHumansIncidenceMaleMiddle AgedProportional Hazards ModelsRegistriesRisk FactorsSick LeaveSwedenWorking ConditionsMusculoskeletal SystemPhysical ExertionSickness absence

Identifiers

PMID42521499
PMCPMC13539868

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.