Evidence map›Paper›PMID 42520484›Full record

ArticleClinics (Sao Paulo, Brazil)2026

Robotic surgery in gastrointestinal cancers: short-term clinical outcomes and micro-costing analysis from a reference oncologic center.

Ricardo Zugaib Abdalla, Antônio José Rodrigues Pereira, Ivan Cecconello, Leticia Souza Rego, Paulo Herman, Ulysses Ribeiro Junior

Registry-linked trialAbstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02292914 (Prospective Analysis of Robot-Assisted Surgery), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02292914 naunknown statusnot on this map

Prospective Analysis of Robot-Assisted Surgery

TypeinterventionalSponsorInstituto do Cancer do Estado de São PauloRan2014 to 2020Enrolled1,120ConditionsEsophageal Cancer, Gastric Cancer, Pancreatic Cancer, Rectal CancerArmsRobot-assisted surgery, Conventional Surgery
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ricardo Zugaib AbdallaFaculdade de Medicina do Hospital das Clínicas da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil; Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, SP, Brazil. Electronic address: ricardo.abdalla@hc.fm.usp.br.
Antônio José Rodrigues PereiraFaculdade de Medicina do Hospital das Clínicas da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
Ivan CecconelloFaculdade de Medicina do Hospital das Clínicas da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
Leticia Souza RegoFaculdade de Medicina do Hospital das Clínicas da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
Paulo HermanFaculdade de Medicina do Hospital das Clínicas da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil; Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, SP, Brazil.
Ulysses Ribeiro JuniorFaculdade de Medicina do Hospital das Clínicas da Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil; Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRobotic Surgery (RS) adoption in public healthcare is limited by high costs. The authors evaluated clinical outcomes and micro-costs of RS for Gastrointestinal (GI) cancers at a Brazilian reference center.

methodsA prospective, randomized trial (NCT02292914) compared RS (da Vinci Si) to a mixed comparator arm (laparoscopic/open) for esophagectomy, gastrectomy, and rectal resection. Primary outcomes were Length of Stay (LOS) and per-patient operative costs. Micro-costing followed national guidelines, including deterministic and probabilistic sensitivity analyses. Analyses followed the intention-to-treat principle.

resultsThe authors analyzed 135 patients (65 RS, 70 control). RS significantly reduced LOS in esophagectomy (14.7 ± 8.2 vs. 20.3 ± 7.4 days, p < 0.001) and rectal resection (8.9 ± 2.1 vs. 10.0 ± 2.5 days, p < 0.05); gastrectomy LOS was similar (11.3 ± 3.8 vs. 11.5 ± 4.1). Estimated blood loss decreased by > 50% across all RS procedures (p < 0.05). Oncologic adequacy (R0 rates and lymph node yield) was comparable between groups. No significant differences in major complications occurred. RS increased per-patient incremental costs: esophagectomy +US$ 3,018; gastrectomy +US$ 2,816; and rectal resection +US$ 1,470, with a pooled GI incremental cost of +US$ 2,326 (95% CrI: 1,718-2,944). Proprietary instruments were the primary cost drivers.

conclusionsRobotic GI surgery reduces LOS and blood loss with oncologic outcomes comparable to conventional approaches. However, it carries a significant cost premium (approx. US$ 2,326/case). Whether these clinical gains justify the investment within the public system requires further multicenter studies incorporating long-term quality-of-life data.

Indexed as

Cost-effectivenessGastrointestinal neoplasmsPublic healthRobotic surgical proceduresSurgical oncology

Identifiers

PMID42520484
PMCPMC13446287

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Registered trials

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