Evidence map›Paper›PMID 42519716›Full record

ArticleNeurology. Genetics2026

Reduced Effect of

René Labounek, Matti J Matheson, Corey A Strong, Ashley Petersen, Annamarie Hill, Ann J Robertson, Adam Hansen, Adam D Block, J Neil Henderson, Igor Nestrasil and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology. Genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Neurology. Genetics · 2026
    Article
4 · The record

Corrections and comments

  • Commented on by
    2026
5 · Who and what money

Authors and funding

12 authors.

René LabounekDivision of Clinical Behavioral Neuroscience, Department of Pediatrics, University of Minnesota, Minneapolis.ORCID https://orcid.org/0000-0003-0439-1304
Matti J MathesonDepartment of Neurology, University of Minnesota, Minneapolis.ORCID https://orcid.org/0009-0002-9095-5048
Corey A StrongBois Forte Band of Chippewa, Health Services, Nett Lake, MN.ORCID https://orcid.org/0009-0006-7991-0227
Ashley PetersenDivision of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis.ORCID https://orcid.org/0000-0001-7711-9657
Annamarie HillDepartment of Neurology, University of Minnesota, Minneapolis.ORCID https://orcid.org/0009-0004-5630-2830
Ann J RobertsonDepartment of Neurology, University of Minnesota, Minneapolis.ORCID https://orcid.org/0009-0009-3448-4596
Adam HansenDepartment of Neurology, University of Minnesota, Minneapolis.ORCID https://orcid.org/0009-0001-3083-6373
Adam D BlockDepartment of Neurology, University of Minnesota, Minneapolis.ORCID https://orcid.org/0009-0006-6447-4952
J Neil HendersonDepartment of Family Medicine and Biobehavioral Health, University of Minnesota Duluth; and.ORCID https://orcid.org/0000-0002-9974-4709
Igor NestrasilDivision of Clinical Behavioral Neuroscience, Department of Pediatrics, University of Minnesota, Minneapolis.ORCID https://orcid.org/0000-0002-3833-1484
Christophe LengletCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis.ORCID https://orcid.org/0000-0003-4646-3185
William G MantyhDepartment of Neurology, University of Minnesota, Minneapolis.ORCID https://orcid.org/0000-0003-2096-2461

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Timothy C. Hallstrom · 1998 to 2026
$100.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UM1TR004405 · NCATS · UNIVERSITY OF MINNESOTA · PI Bruce R Blazar, Damien A Fair · 2023 to 2026
$30.8M
TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Mehmet Akcakaya · 2019 to 2026
$11.7M
Dementia prevalence, APOE, and blood-based biomarkers of AD in Native American communitiesR01AG080806 · NIA · UNIVERSITY OF MINNESOTA · PI William G Mantyh · 2022 to 2026
$3.7M
NCATS NIH HHS UM1 TR004405NCI NIH HHS P30 CA077598NIA NIH HHS L30 AG060578NIA NIH HHS R01 AG080806NIA NIH HHS U01 AG024904NIBIB NIH HHS P41 EB027061
6 · The paper itself

Abstract

Background and Objectives: Apolipoprotein E4 ( Methods: We performed a cross-sectional, community-based study in partnership with the Bois Forte Band of Chippewa. Tribal Elders (>54 years of age) were evaluated at the Tribal Nation's health clinic or urban office and were recruited via radio, health fairs, social media, and flyers. We preselected 7 MRI white matter tracts that prior work has shown to be consistently associated with Results: Sixty-two tribal Elders were included. The mean age was 65 years, and the mean Mini-Mental State Examination score was 29. Forty-nine (79%) participants were female, 33 (53%) had hypertension, and 10 (16%) were Discussion: Tribal elders have an attenuated effect of

Identifiers

PMID42519716
PMCPMC13382980

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.