Evidence map›Paper›PMID 42519683›Full record

ArticleClinical case reports2026

A Case of Meige Syndrome in a Pediatric Patient With Schizophrenia.

Kosuke Mizobuchi, Hisashi Tanii, Koji Kanai

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kosuke MizobuchiHinaga General Center for Mental Care Yokkaichi Japan.
Hisashi TaniiHinaga General Center for Mental Care Yokkaichi Japan.
Koji KanaiCenter for Physical & Mental Health Mie University Tsu Japan.ORCID https://orcid.org/0000-0003-1781-6033

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term treatment with multiple antipsychotic medications for schizophrenia may increase the risk of developing tardive dystonia, including Meige syndrome. Although clozapine has been suggested as a way of improving dystonia symptoms, there is no established consensus regarding its use in pediatric patients with treatment-resistant schizophrenia, and careful consideration is required. A 12-year-old boy with schizophrenia experienced blepharospasm and oromandibular twitching while undergoing treatment with multiple antipsychotic medications. We stopped giving him the same medications that had been used during his previous hospitalizations (risperidone, olanzapine, aripiprazole, lurasidone, and paliperidone, paliperidone palmitate (a long-acting injectable), asenapine, and blonanserin). We then started giving him clozapine, gradually increasing the dose to 125 mg. Following this treatment intervention, the dystonic symptoms resolved completely, and the psychiatric symptoms stabilized.

Indexed as

clozapineMeige syndromepediatric patientschizophreniatardive dystonia

Identifiers

PMID42519683
PMCPMC13381720

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.