Evidence map›Paper›PMID 42519616›Full record

ReviewInfectious diseases & immunity2026

Opportunities and challenges in achieving a functional cure for HIV.

Wanying Zhang, Mo Zhou, Jingliang Chen, Yizi He, Linghua Li

Abstract readReview
In one paragraph

Review in Infectious diseases & immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wanying ZhangGuangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, China.
Mo ZhouGuangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, China.
Jingliang ChenGuangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, China.
Yizi HeGuangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, China.
Linghua LiGuangzhou Medical Research Institute of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human immunodeficiency virus (HIV) epidemic poses a significant threat to global human health annually. Although antiretroviral therapy can control HIV viremia and delay disease progression, it cannot eliminate the viral reservoir. People living with HIV must rely on antiretroviral medication for their entire lifetime. HIV establishes a persistent viral latent reservoir, which remains an enormous challenge in eradicating HIV infection. With advancements in HIV research, many strategies have emerged to target cells harboring latent HIV. A functional cure for HIV has been proposed as a promising and pragmatic strategic objective. In this review, we provide an overview of current strategies and the latest research progress in the field of HIV cure development, highlighting the opportunities and challenges associated with finding a functional cure for HIV.

Indexed as

Functional cureHIVLatent reservoir

Identifiers

PMID42519616
PMCPMC13384682

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.