ArticleClinical optometry2026
Ocular Dimensional Changes After 12 Months of Orthokeratology and Single-Vision Spectacle Use: A Three-Dimensional Magnetic Resonance Imaging Study.
Article in Clinical optometry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Purpose: This study investigated the 12-month impact of orthokeratology (Ortho-K) treatment on eyeball dimensions using magnetic resonance imaging (MRI). Results were compared with single-vision spectacle wearers (SVS). Patients and Methods: A total of 70 Chinese schoolchildren (mean age: 8.31 ± 0.47 years) with myopia were assigned to Ortho-K (n = 45) and SVS (n = 25). Baseline spherical equivalent (SE), visual acuity (VA), and flat keratometry (FK) were measured. MRI was performed at baseline and at 12 months to measure three-dimensional ocular dimensions, including longitudinal axial length (LAL), horizontal width (HW), and vertical sagittal height (VSH). Standard slit-lamp examinations ensured ocular health at all follow-up visits. Results: At 12 months, the Ortho-K group showed significant reductions in SE and FK (p < 0.001), whereas the SVS group exhibited a significant increase (p < 0.05). LAL was significantly shorter in the Ortho-K group compared to SVS (p < 0.05). Although individual HW and VSH did not reach independent significance, repeated measures analysis of variance confirmed significant between-group differences in global eyeball shape over 12 months (p < 0.05). Correlation analysis revealed a significant association between SE and LAL in the SVS group (p < 0.05). In the Ortho-K group, SE showed no significant correlation with ocular dimensional changes (p > 0.05). In contrast, FK in the Ortho-K group demonstrated significant correlations with all dimensional parameters (p < 0.05), a pattern not observed in the SVS group. Conclusion: Findings indicate that myopic progression in the SVS group is primarily driven by axial elongation, whereas refractive changes in the Ortho-K group arise from corneal reshaping. Over 12 months, Ortho-K wear modifies ocular dimensions and inhibits AL elongation more significantly than SVS, providing a structural basis for controlling myopic progression.
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